Clinical Observation On The Therapeutic Effect Of Jianpi Bushen Lishi Recipe On G1-G3 Proteinuria Of Diabetes Nephropathy(Spleen Kidney Qi Deficiency With Dampness Type)

Objective:To observe the clinical efficacy of Jianpi Bushen Lishi Recipe in the treatment of G1-G3 proteinuria(spleen kidney qi deficiency dampness type)of diabetes nephropathy.Methods:Using randomized controlled trial method,according to the random number envelope into our nephrology,endocrine outpatient and hospitalization in diabetic nephropathy G1-G3 proteinuria(spleen and kidney qi deficiency with wet)a total of 60 cases,randomly divided into 30 cases,test group 30 cases,control group to western medicine,test group on the basis of the control group to spleen kidney wet side.After the treatment period of 8 weeks,the changes of TCM symptom integral,urinary microalbumin(UmAlb),urinary creatinine(UCr)and its ratio(UACR),24 hours urine protein,blood creatinine(CR),urea nitrogen(BUN),blood uric acid,fasting blood glucose(FBG),glycated hemoglobin and statistical analysis.Results: After a 8-week treatment cycle,the treatment of spleen and kidney and dampness was better than conventional treatment for diabetic nephropathy patients with G1-G3 proteinuria(spleen and kidney qi deficiency)combined with conventional medicine.By comparing before and after treatment,there was no difference between TCM symptoms,urinary microalbumin(UmAlb),urinary creatinine(UCr)and its ratio(UACR),24-hour urinary protein,fasting blood glucose(FBG),HBG,blood creatinine(CR),urea nitrogen(BUN),and blood uric acid(P>0.05).Conclusion: Only invigorating spleen and kidney and promoting dampness can reduce spleen and kidney qi deficiency and G1-G3 proteinuria of wet diabetic nephropathy,reduce blood sugar and improve TCM syndrome score,which may be beneficial to delay diabetic nephropathy.