The Relationship Between TCM Syndrome Types And Risk Factors And Medication Rules In The Acute Stage Of Ischemic Stroke In Changde Cit

Objective: To explore the TCM syndrome types of ischemic stroke in acute stage in Changde,the relationship between TCM Syndrome types and related risk factors and the regularity of drug use.Methods: Clinical data of 200 patients with acute ischemic stroke were collected from January 2020 to June 2021 from the first Chinese Medicine Hospital in Changde,the Chinese Medicine Hospital in Shimen County,and the Chinese Medicine Hospital in Taoyuan County,collected the Sex,age,blood lipid,fibrinogen,homocysteine and TCM syndrome types of the patients to analyze whether there were correlation in different indicators.In this paper,the prescriptions of the common types of traditional Chinese medicine were sorted out,and the frequency statistics of the prescription drugs and their properties,flavors and Meridians were made,and the rules of medication were analyzed by association rules and systematic clustering.Results:1.There are three types of syndrome in 200 cases:wind-phlegm Stagnation Syndrome,phlegm-heat-fu Syndrome and qi-deficiency-blood-stasis Syndrome.The incidence of wind-phlegm stagnation syndrome is the highest,followed by phlegmheat-fu Syndrome and qi-deficiency-blood-stasis syndrome(76.5%,13.0%,10.5%).The distribution of blood lipid(TC,TG,HDL-C,LDL-C)and HCY in TCM syndrome types were significantly different(P<0.05).TC,TG and HCY increased significantly in windphlegm-stasis Syndrome and phlegm-heat-fu Syndrome.There was no significant difference in the distribution of TCM syndrome types among gender,age and FIB(P>0.05).2.Totally 153 prescriptions were involved in prescriptions of acute stage with ischemic stroke,including 118 types of Chinese materia medica were used,45 types of Chinese materia medica were with the frequency≥10.The high-frequency drugs in the prescription are Shichangpu(Acorus Tatarinowii),Banxia(Pinellia),Gancao(Liquorice),Baizhu(Macrocephala Rhizoma),Tianma(Tall Gastrodia Tuber)etc.The drug were mainly of cold,warm,flat,kam,bitter and skinwell flavor,and the channel tropism of drugs mainly distributed to the liver,lung,spleen,stomach.The drug combination with strong correlation was Fuling-Banxia etc.Conclusion: The indexes of blood lipid and homocysteine in acute stage of ischemic stroke in Changde were significantly correlated with wind-phlegm-stasis Syndrome and phlegm-heat-fu Syndrome.The treatment of wind-phlegm-stasis Syndrome in acute stage of ischemic stroke in Changde is mainly to dispel wind-phlegm and dissipate phlegm,and also invigorate the spleen,remove dampness,invigorating Qi and promoting blood circulation.