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Clinical And Experimental Studies On The Treatment Of Chd Of Asthenic Qi Blood Stasis With Fufang Huangqi Wutang Infusion

Posted on:2002-02-16Degree:DoctorType:Dissertation
Country:ChinaCandidate:Y Y WangFull Text:PDF
GTID:1104360032456546Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Fufang Huangqi Wutang infusion is an effective drug that be summed up by my tutor.The principle of supplementing qi and activating is the therapetic principle which treating CHD of asthenic qi blood stasis. In this treatise, through animal experiments and clinical studies ,we can see the mechanisms of how Fufang Huangqi Wutang infusion can play an influential role in prevention and treatment of CHD can be deeply probed into. The results show that: 1. Fufang Huangqi Wutang infusion manifest the anti-damage function to myo cardial ischemia; 2. Fufang Huangqi Wutang infusion can obviously improve cardiac energy metabolism; 3. Fufang Huangqi Wutang infusion can protect vascular endothelial dysfunction; 4. Fufang Huangqi Wutang infusion can accelerate and fortify the construction of bypass circulation and the regeneration of new capillaries; 5. Fufang Huangqi Wutang infusion may depress or disrupt the over-apoptosis procedure of myocardial cells so that the cardiac muscles are protected since apoptosis mechanism may play a significant role in the pathological procedure in myocardial is c hem i a injury; 6. Fufang Huangqi Wutang infusion may depress or disrupt the procedure of cell apoptosis by regulating the expression of fas-gene and Bcl-2 gene, since the two may take an active part in the procedure of myocardial cell apoptosis; The clinical studies show that Fufang Huangqi Wutang infusion have protect endothelial cell function , it can debate ET,increasa NO. Fufang Huangqi Wutang infusion have anti-myocardial ischemia function, it can debate MDA,increase NO. The research results shownabove suggest that Fufang Huangqi Wutang infusion can play a significant anti-damage role to myocardial ischemia through a mlltiple-channelled synthetically mechanism.
Keywords/Search Tags:FufangHuangqiWutanginfusion, Coronary Heart Disease (CHD), The principle of supplementing qi and activating, Animal experiment, Clinical study
PDF Full Text Request
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