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Experimental Research On The Skin Antiaging Function Of Tianzhen Zhuyan Pill

Posted on:2003-09-27Degree:DoctorType:Dissertation
Country:ChinaCandidate:H LiangFull Text:PDF
GTID:1104360065960140Subject:Traditional Medical Formulae
Abstract/Summary:PDF Full Text Request
0n the basis of the research carried out into skin agingby experts in medica1 science, ancient and modern, as we11as a further discussion on the mechanism of skin aging,Tianzhen Zhuyan Pi 11 is created, whose main funct ion is tosupp1ement the kidney. In addition, it can a1 so supp1ementB1ood and 0j, even de1ay aging process. 1ts aim is to combinefirm1y Tradi t iona1 Chinese mediclne wi th modern techno1ogyby a series of systemat ic sci ent if i c researches and designs.0n the who1e, thi s di ssertat ion is a comprehensive researchwhich ranges a wide field: consti tuents, manufacturingequipment, qua1 ity, and medica1 effect experiments ofTianzhen Zhuyan Pi 11. The content of experiments ranges frombiocheml stry, h isto1ogy, patho1ogy, pharmaco 1ogy tocyto1ogy and mo1ecu1ar bio1ogy. The data of experimenta1items inc1ude the fo11owing: activity of S0D in skin andserum of o1d rats, MDA 1eve1, The content of 1ipofuscin in1iver, The content of hydrooxypro1in in skin of o1d rats;sexua1 organ weight. Capac i ty of water absorpt ion andestrogen of o1d fema1e rats l the content of 1L--2 in serum,the content of water in skin, form changes, apoptosis andre1evant gene formu1a of o1d rats, manufacturing techni gues,qua1 ity contro1 and stabi 1 ity. 1n conc1us1on, the antiagingfunction of Tianzhen Zhuyan pi11 may be re1ated to thefacfors be1ow: stimuIating the activity of the content ofS0D in skin and serum; strengthening the abi1ity to c1earfree radica1 i decreas1ng the content of MDA. Hyp in skin and2xxu9 ffeMxdewdegurttexLf in 1 iver i postponing the format ion and accumu1at ion of. Lf, increasing the content of IL--2, profnoting the skinimmunity power, increas lng the capac ity of water ho1ding of- skin; perfecting the structure of decaylng skin i inducingup the apoptosis; checking the gene expression of Bc1--2 andstimu1ating the positive expression of fas gene. In one word,it provi des effi c ient and powerful theoret ica1 support andscient if ic data for the wide app1 icat ion of Tianzhen ZhuyanP i 11.
Keywords/Search Tags:skin aging, Tianzhen Zhuyan Pill, S0D, MDA, Lf, Hyp, E2, IL-2, apoptosis, Bc1-2, fas
PDF Full Text Request
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