Magnetic Stimulation Motor Evoked Potential In Normal Subjects And Cases With Multiple Sclerosis And Guillain-Barré Syndrome

Magnetic stimulation motor evoked potential (MEP) is a new technique developed recently and it can measure founction of motor pathways, but the clinical applications of MEP hare not fully explored.MEP studies were carried out on normal subjects and patients with multiple sclerosis (MS) and Guillain-Barre Syndrome (GBS). Both of them are autoimmune diseases. The central motor pathways and the peripheral motor pathways are involved in MS and GBS respectively. These two diseases are not uncommon in neurological field, GBS ha6 been shown prevalence in some areas in China during the recent years.The main purpose of the studies in clinical applications are to â‘ approach pathophysiological mechanism of MEP changes in different lesions of motor pathways; â‘¡ study the correlation between electrophysiological measurements and clinical features, and the correlations of different electrophysiological testings; â‘¢ try to find a method which is high sensitivity and suitable for clinical diagnosis, differential diagnosis and observation of curative effect.I, The study of MEP normative valuesNormative data were obtained on 67 normal subjects, men 31 and women36. No significant side effects were presented.The results showed: cortex-to-target muscle latencies measured 20.4 ± 1. 5mS (abductor digiti minimi), 26.7±1.7mS( tibialis anterior). Central motor conduction time(CMCT)between cortex and C₇, L₄ measured 8. 8±1.4mS and 13.9±1.4mS respectively. Latencies...