Studies On The Chemical Constituents And Bioactivities Of Nigella Glandulifera Freyn Et Sint. And Carthamus Tinctorius L.

Abstract: This doctoral dissertation dealed with the phytochemical and pharmacological studies on two medicinal plants, Nigella glandulifera Freyn et Sint. and Carthamus tinctorius L.. In the meantime, this dissertation reviewed the chemical and pharmacological reseach works about Carthamus genus.Nigella glandulifera Freyn et Sint., a plant of Nigella genus in Ranunculaceae family, is widely distributed in Xinjiang, Yunnan and Xizang. In order to find some better compounds with antitumor activity, we made a systematic research on this plant.Using kinds of chromatography technique, 16 compounds were isolated, on the basis of chemical methods and spectroscopic analysis, their structures were determined as Nigeglanine (NG1), Nigeglapine (NG2), Fuzitine (NG3), Nigelloside (NG4), Nigeglanoside (NG5), Nigellamose (NG6), a-Hederin (NG7), 3-O- [β-D-xylopyranosyl-(1→3)-α-L- rhamno-pyranosyl -(1→2)- α-L- arabinpyranosyl]-hederagenin (NG8), Sucrose (NG9), Hexacosanoic acid (NG10), Stearic acid (NG11), 1-Eicosene (NG12), 1-O-hexadecanolenin (NG13), β-Sitosterol (NG14), Daucosterol...