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Studies Of The Constituents And Biological Activities Of Aronia Melanocarpa Elliot And Polygonum Capitatum Buch-Ham Ex D. Don

Posted on:2007-03-01Degree:DoctorType:Dissertation
Country:ChinaCandidate:M YuFull Text:PDF
GTID:1104360185989157Subject:Natural medicinal chemistry
Abstract/Summary:PDF Full Text Request
1. Aronia melanocarpa Elliot, belonging to Rosaceae, is a low wood origin of the northeast of America. It was introduced and cultivated in China from the 1990's. The fruits and the extracts of Aronia melanocarpa have been reported to have antioxidant, anti-inflammatory, anticancer and antihyperglycemic activities, and also have the therapeutic effects on cardiovascular diseases.From the ethanol extracts of the seedlings and the fruits of Aronia melanocarpa Elliot, 31 compounds were isolated by various chromatographic and recrystallized methods. On the basis of analysis of NMR, MS data, measurement of physico-chemical characters and chemical methods, the structures of 28 compounds, which belonging to triterpenes, flavonoids and so on, were identified as: 16-O-acetyl-21-O-angeloyl theasapogenol A 3-O-[β-D-galactopyranosyl (1→2][β-D-xylopyranosyl(1→>2)-α-L-arabinopyranosyl(1→)3)]-β-D-glucopyranosiduronic acid (1), 16,28-O-diacetyl-21-O tigloyltheasapogenol A 3-O-[β-D-galactopyranosyl(1→2)][β-D-xylopyranosyl(1→2) -α -L-arabinopyranosyl(1→3)]-β-D-glucopyranosiduronic acid (2), friedelin (3), betulinic acid (4), betulin (5), 23-hydroxybetulinic acid (6), betulinic acid 3β-caffeate (7), 23-hydroxybetulinic acid 3β-caffeate (8), ursolic acid (9), 2α-hydroxyoleanolic acid (10), 3β-O-acetylursolic acid (11), 19α-hydroxyursolic acid (12), 2α,3α-dihydroxyursolic acid (13), 2α, 3α,19α-trihydroxyursolic acid (14), (-)-epicatechin(15),...
Keywords/Search Tags:Aronia melanocarpa Elliot, Polygonum capitatum Buch-Ham ex D. Don, chemical constituents, anthocyanins, antibacterial action, anti-inflammation
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