The Red Tongmai Capsule Treatment Of Hyperlipidemia (blood Stasis Syndrome) Clinical Observation

The coronary heart disease (CHD) and stroke are the main diseases harming themankind healthiness. Though the incidence rate of CHD in our country is lower thanthe west developed countries, in most part of our country, particularly the north orrelatively developed area, this illness tends to be more and more and is becoming themain cause of death. Therefore, how to prevent and cure of CHD and stroke is also thefocus of the medical research. Based on the close relationship with the atherosclerosis,there is little doubt that hyperlipidemia is a major, independent risk factor formorbidity and mortality of cardiovascular disorders. With the development of livinglevel, the morbidity of the hyperlipidemia tends to be increasing. How to prevent andcure it has become a focus. Two parts in the thesis: document reviews and clinical research. Document reviews: In this part, opinions of traditional Chinese medicine (TCM)and western medicine in the etiology, pathogenesis, differentiation, epidemiology andthe therapy of hyperlipidemia were discussed, including prescription according todiseases, single herb medicine, acupuncture and moxibustion, statin therapy, fibratetherapy and others. In this paper, we have reviewed those trials that have made a majorimpact on the practice of clinical cardiology within the last 10 years. We can draw aconclusion that the treatmention of liporegulation should take more important positionin the prevention and therapy of CHD and stroke. Clinical research: Objective: To determine the effect and safety of Chi Dan TongMai Capsule, which is made up of Radix Salviae Miltiorrhizae, Radix Paeomiae Rubra,Radix polygoni Multiflori, taken by 80 patients with hyperlipidimia belonged tostagnation of blood. Methods: A 6-week randomized double-blind doubleimitate-control parallel observational study. Demographics, cardiac risk factors, andlipid profile were collected. Results: Compared with baseline values, Chi Dan TongMai Capsule has reduced plasma total cholesterol levels and TG , LDL-C ,ApoB.Compared with Zhi Bi Tuo Capsule, Chi Dan Tong Mai Capsule has thesignificant effects in symptom remission. Conclusions: Results of clinical research ofChi Dan Tong Mai Capsule demonstrate that an improvement in lipid profile resultsand significant effects in symptom remission and there has no serious side effects. In summery, it is concluded that Chi Dan Tong Mai Capsule is effective and safefor the patients with hyperlipidimia and with manifestation of stagnation of blood, andit suggests that "activate blood method" is one of the most effective methods to curehyperlipidimia. Furthermore, it is worthy to be studied deeply.