Nitric Oxide Is Involved In Radionuclide Ventriculography Preliminary Study Of Congenital Heart Disease Pulmonary Hypertension In Patients With Heart Function And Pulmonary Vascular Lesions

Introduction and ObjectiveThe interaction between right and left ventricles, the effects of one ventricular function on the other, was throughout the septum, common muscle fiber, and the pericardium mediated by pulmonary circulation. Patients of congenital heart disease with left to right shunt have increasing pulmonary blood flow, which may lead to pulmonary hypertension (PH). The pressure load resulting in right ventricular function impairment and left ventricular function would be involved. Relief of afterload of right ventricle by reducing pulmonary hypertension may dramatically improve both ventricular function. The use of inhaled nitric oxide as a selective pulmonary vasodilator has expanded to include patients with congenital heart disease and pulmonary hypertension. The therapeutic and diagnostic methods of inhaled nitric oxide play an important role in management of patients with pulmonary hypertension.The aim of our study was to determine the effect of inhaled nitric oxide on right and left ventricular function and evaluate the degree of pulmonary hypertension reversibility by the right ventricular function responses following inhaled nitric oxide in patients with CHD and pulmonary hypertensionMethodsA delivery device qualified for 30 ppm inhaled nitric oxide at oxygen FiO₂ 0.25was established and ERNA obtained the sensitive indices of the diastolic function and systolic function— peak filling rate (PFR) and ejection fraction (EF).