Study On The Thrombophilia Factors Of Venous Thromboembolism Patients And On Relationship Between Factors And TCM Syndrome Types

Objective:to study the clinical features of hereditary and acquired thrombophiliafactors of venous thromboembolism(VTE) patients,and to explore the correlation betweenthe two factors,and to analyse the relationship between the factors and TCM syndrometypes.Methods:Based on the detection of the activity and (or) antigen ofantithrombin-â…¢(AT-â…¢),protein C(PC),protein S(PS),plasminogen(PLG) andhomocysteinemia(Hcy),we can calculate the ratio of every hereditary thrombophilia.Through the clinical questionnaire,we can obtain the features of corresponding acquiredfactors which are closely related to each hereditary factor.100 cases of deep venousthrombosis (DVT) are devided into two groups in random,one is blood stasis group,oneis pathogenic dampness-heat group.Based on the analysis of anticoagulant andprocoagulant factors between the two types,we can screen the optimal indicators tojudging the type.Results:there are 48 cases attributed to hereditary thrombophilia in the142 VTE patients.The PS deficiencies and hereditary hyperhomocysteinemia(HHcy) arethe main factors in the hereditary thrombophilia.The trauma,long-term bedridden andoperation are the important impact factors which evoke the VTE to the thrombophiliapatients.The age is the independent impact factor to the thrombophilia patients.Throughthe analysis,the activity and antigen of AT-â…¢and PC,antigen of Hcy are the screeningindicators to judging the TCM syndrome types.Conclusion:The PS deficiencies andhereditary hyperhomocysteinemia(HHcy) are the main factors in the hereditarythrombophilia.The important roles of acquired factors which evoke the VTE to thethrombophilia patients should be paid more attention to.The anticoagulant andprocoagulant factors may be the objective basis on the microscopic syndrome differentionand enrich the connotion of syndrome diffenention.