Research On Multi-Signals Synchronous Detection Of Systemic & Pulmonary Circulation System And Its Quantitative Analysis By Precise Pulse Condition

The pulse condition of human body comes from heartbeats,which is one of the important body characteristics,and reflects the life activity.Containing abundant physiological and pathologic information in the pulsation of pulse waves,not only the ancient Chinese medicine had already diagnosed a disease by feeling the pulse very early,but also the ancient Greek had recorded the human body pulse wave going far back to ancient times abroad.The Chinese medicine works:《Inner Canon of Huangdi》,《Canon of Pulse》and《Study of Vein by Binhu》are the typical technical development representatives of the ancient vein diagnoses.With the progress of modem medicine,Noninvasive detection technique has a rapid development.People's research to the pulse wave is more scientific and thorough,not only the detecting means have been diversified,but also the analytic techniques already have headed from qualitative analysis to quantitative analysis.Related researches have already been unlimited at the traditional Chinese medicine theories, which are developing to integrative research in multi-fields such as physiology, pathology,anatomy,biomechanics,hemodynamics,computer science,mechanics and electronics etc.The study of vein has already become a systems engineering gradually,which was subjected to a high value of the medical science field inside and outside.Within the current pulse-condition detection methods,the pulse transducer design and its signal information analysis are two sticking points.On the one hand, the means of pulse-condition collection are more single,the design of its transducer generally is limited to recording a press sphygmogram and still falls through the collection of pulse-condition's 3D information dynamically;On the other hand,the detecting sensors give priority to a pressure type.Not only its placement is more troublesome,but also the problems still have not been easy to resolve,such as disturbing pulse-condition,low accuracy and bad stability etc.Especially to the detection of venous pulse wave,these problems are still outstanding.This paper more and thoroughly discusses the principle of non-contact pulse-condition detection with laser,which based in great quantities of experiments,and particularly presents a special accentuation of the importance to detect and research the right heart system.For the first time,choosing the TRI-PULSE-BALL(where the right internal jugular vein,right external jugular vein and right subclavian vein converge at a saccate ball located in the right central venous.) as the ideal sampling dot of vein pulse signal,which is optimal and the nearest point of vein system in the whole body to detect right atrium system.It systematically explored the laser detection technology of pulse,and invent three practical non-contact vein transducers,which can solve the conundrum of "Breath Interference" and has been supported by a grant from the National Natural Science Foundation of China.This thesis has carried on mathematical description and analysis in a view of TRI-PULSE-BALL venous pulse wave.For the first time,the one by one wave sub- normalized method is used to fit the venous pulse wave of TRI-PULSE-BALL with Gauss function simply,which achieved good results; Meanwhile,the physiological connotation of the venous pulse wave and its characteristics is studied.It accordingly offers a line of thought to the in-depth research of venous pulse wave.Among current techniques of sphygmus wave analysis,the detection theory and technique of "Pulse Diagram Method" which had been created by Zhang Daxiang is regarded as a milestone of phase.Aiming at the pathological mutation of a fine pulse-condition,this thesis gives some nonlinear methods as multiwavelets to carry out multidimensional signals distilling,the characteristic point of pulse-condition catching,signing and analyzing,which based on the research of Zhang Dazing and his team.It can restrain the noise,pick up the useful signal and realized the feature point automatic signing with the wavelet methods. Compare with existing methods,the feature point located by the new method is more accurately,and settles a base for analyzing the pathologic aberrance effectively. In the end,the paper advances the feature point marking and its nonlinear analysis method with wavelet,which based on a multi-signal synchronous detection such as artery pulse wave,vein pulse wave,electrocardio and cardiac sound.In the light of the foregoing research about pulse laser transducer and multidimensional nonlinear analysis,the paper gives the design of a new instrument to detect and analyze the systemic,pulmonary circulation system with a multi-signal,synchronous,noninvasive detection and quantitative analysis method,by the way,designed the instrument system motherboards.The main works include:1) Designed the PCB of signal processing board,the analyzing board and a prototype of the instrument;2) Put forward wavelet arithmetic methods to deal with multi-signal synchronization and wavelet singal extraction algorithms under the DSP+ARM structure to raise the code efficiency;3) Writed the host procedure,carried out the detection,record,sign and analysis of artery pulse wave,vein pulse wave,electrocardio and cardiac sound.Meanwhile,it computed and outputted 32 parameters.The results show that the prototype of the testing system has higher accuracy,more comfort and higher reliability.