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The Research Of The Factors Related Of TCM Syndromes In The Type 2 Diabetes Mellitus Complicated With Cardiopathy Disease

Posted on:2010-06-04Degree:DoctorType:Dissertation
Country:ChinaCandidate:S H LaiFull Text:PDF
GTID:1114360275966108Subject:TCM clinical basis
Abstract/Summary:PDF Full Text Request
Diabetes is a serious threat to the health of all humanity a common endocrine and metabolic diseases.Is a complex etiology more than the basic patbophy-siology of its absolute or relative lack of insulin secretion caused by fat and protein sugar And other metabolic disorders.In both developed and developing countries,with the improvement of living standards and population exacerbated by aging,the incidence of diabetes is increasing year by year.At present,the World health Organization has diabetes Serious impact on human health as the No.3 major diseases,but also the world's one of the most common chronic diseases.Among them,the most common type 2 diabetes,accounting for all diabetic patients 90%,Diabetes complications,In which the complexity of chron-ic complications of the disease,refractory,harmful,and can lead to heart,brain,kidney,eye,surrounded by the body,such as multi-system and multi-organ damage,occult onset,showing progressive development of the early difficult to find,to a certain stage of development,its treatment of poor,disabled and even death.High prevalence rate of diabetes as well as caused by the size of clinical vascular complications has caused widespread concern,especially in diabetic heart disease,diabetes by chronic complications in the most common and most serious one,it threatens people's health and lives,but also to Social cause huge economic burden.Diabetic heart disease(Diabetic Cardiopathy,DC)is the sugar in diabetic patients,such as substit-uting fat,disorder based on or associated with complications of heart disease,mainly related to the heart of large,medium and small and microvascular,including non-specific coronary atheroscler otic heart disease,diabetes-specific cardiomyopathy,diabet ic autonomic neuropathy tangled disorder-induced arrhythmia and cardiac dysfunction,may also include those who have high blood pressure hypertension heart disease.clinical manifestations canbe asymptomatic to severe arrhythmia,cardiogenic shock or acute myocardial infarction,such as with.Age at onset of light,the rapid development of high prevalence and mortality,high-risk arrhythmias ,heart failure and sudden death.Because of its complex etiology,but also has unique pathophy-siological changes,the clinical research and treatment with certain difficulties.At present,most scholars agree with diabetes have heart disease is an independent,but lack of specificity of quantitative indicators to assistin diagnosis,which remains the main directions of future research.Objective:(1)The purpose of this research is that Diabetic Cardiopathy and diabetes mellitus compared to the etiology,pathogenesis,the main disease and Syndromes have different characteristics,according to thecharacteristics of these clinical syndromes based on the understanding of the ransformation of the disease.(2)The incidence of diabetes as a result of hidden Diabetic Cardiopathy ,clinical practice of modern medicine make full use of advanced inspection of hand Paragraph of this diseasespecific indicators for the relevance of the analysis and comparison,to find a non-invasive and can reflect the early Change the characteristics of diabetic heart sensitive and specific indicators. To early diagnosis and treatment.Methods:(1)Sub-group method:The Search for the interception of calculator Guangzhou University of Traditional Chinese Medicine first affiliated hospitalof the past five years diabetes cases in order to meet a total of 315 cases.And sub-group of diabetes and complications of heart disease(Diabetic Cardiopathy Group)with complications of heart disease group(diabetic group). Diabetic Cardiopathy and diabetes mellitus common risk factors.specific indicators and the performance of TCM List of hospital medical records by the researchers based on fill.(2) observation of the project:Record the relational data such as sexual ,age,the course of diease,blood pressure,FBG,HbAlc,TC,TG,HDL-C, LDL-C,ApoA,ApoB,UA,BUN,Creatine,B-OHB,ESR,CRP.Results(1) The analysis of the general situation:The gender dimension in Diabetic Cardiopathy disease and diabetes in the group the difference was not statistically significant.However,two groups of male With the number of women.(2) The analysis of the major risk factors for diabetes mellitus complicated with Diabetic Cardiopathy①high blood sugar:in this research,FBG levels in diabetic group and diabetic group of Diabetic Cardiopathy there was no significant difference. HbAlc levels and diabetic Cardiopathy t disease and diabetes in the group differences there was a significant(P<0.05).FBG with HbAlc values higher in the diabetic group.②Hypertension:The results of this research,blood pressure values in the diabetic group and Diabetic Cardiopathy disease group compared the two groups no significant difference,however,in patients with systolic blood pressure higher than the ordinary.③Dyslipidemia:results show that TC between the two groups TC,TG,ApoA,ApoB,HDL-C,LDL-C Comparison of the difference was not significant in stati-stical significance.④CRP:The results of this research,Diabetic Cardiopathy disease and diabetes group than in the two groups moreno significant difference,but CRP levels were significantly elevated. ⑤age,the course of diease:The results of this research show that age group and diabetes in the diabetes group than in heart disease than there was a significant difference of statistical significance,therefore,the greater the age of their diabetes the greater the risk of heart disease,length inthe course of Diabetic Cardiopathy disease and diabetes in the group there was no significant difference statistically significant,but diabetes of longer Diabetic Cardiopathy disease group.(3) The analysis of other risk factors for diabetes with Cardiopathy disease:①The analysis of UA,BUN,CREA:The results of this Research showed that the level of UA,BUN,CREA Diabetic Cardiopathy disease and diabetes in the group there was no significant difference statistically significant.However ,in order to UA,BUN,CREA group diabetes higher levels of Diabetic Cardiopathy.②The analysis of B-OHB,ESR:The results of this Research showed that B-OHB,ESR levels in diabetic group and Diabetic Cardiopathy disease group there was no significant difference in statistical significance.③different card-based comparison of disease:Diabeticgroup and Diabetic Cardiopathy disease group Deficiency of(EHDYG),(DBQYG),(DBYYG) comparisons.The results showed that,the number of diabetic patients: Deficiency of(DBQYG) was followed by a(EHDYG),deficiency by(DBYYG).Group of Diabetic Cardiop- athy:a few more cases of(DBQYG)followed by deficiency of(DBQYG) andsyndrome of heat due to deficiency of(EHDYG).Conclusion:The results of the analysis indicate of This issue by comparing:(1) The main reason for the Cardiovascular diabetes of the hypertension and high blood sugar.(2) The external factors for the Cardiovascular diabetes of smoking and drinking.(3) The internal factors for the Cardiovascular diabetes ofold age.(4) The basic pathogenesis for the Cardiovascular diabetesof abnormal lipid metabolism(5) The pathological process for the Cardiovascular diabetes of chronic inflammatory response(6) TCM syndrome distribution:The type 2 diabetes mellitus complicated with Cardiopathy disease type distribution of TCM syndrome have a certain regularity.(DBQYG)which appears the highest rate that chronic diabetes,in Yang injury due to wear and tear qiand yin two injuries,and with the continuous development of the disease,heart workers injured body,and its use gradually declined,loss yin and yang.(7) The main syndrome of the evolution the results showed that syndrome differentiation in the TCM of chest pain and chest tightnes and palpitations and shortness of breath,that the occurrence(DBQYG) appears in the highest .Chinese medicine practitioners agreed that more due to(DBQYG),Qi deficiency is unable to run due to the promotion of blood stasis,deficiency dry hot,hard body fluid,less fluid loss and can not set the blood to run ,leading to blood stasis within the stop.Ultimately caused by the pulse of (DBQYG) Network do not and,in patients with chest pain chest tightness, heart palpitations and other emerging.
Keywords/Search Tags:type2 diabetes mellitus, Diabetic cardiopathy, syndrome of Chinese Traditional medicine
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