| ObjectiveThe ecchymosis research is glorious in the traditional traditional Chinese medicine history,the deep pool source and course is long."blood stasis" the concept also therefore has the narrow sense and the generalized difference.The narrow blood stasis(ecchymosis) is refers to the hematocele,to keep the pathology product which the blood,the wicked blood,the extravasated blood,the dried blood,the dead blood,the defeat blood, the blood movement impeded stagnate.The generalized blood stasis has included the narrow ecchymosis, makes a general reference by the phlegm is muddy,the indigestion,plague,the summer heat,cold-damp, factors and so on sentiment will impetusing cause the blood flow to be impeded,either accumulates in the arteries,either overflows outside the arteries,either forms the thrombus,as well as organism nature,the ingredient has the changer.The blood stasis is many disease extremely common basic pathological changes and the common morbid state,sends regarding disease tosses and turns turns over to have the material effect. Has Zhu Bingduo the stasis,sickness long blood stasis,the stasis to live wet muddy,the stasis anti- vitality,the stasis for a long time to enter winds and so on characteristics.The traditional medicine thought that the tumor is one kind of body-wide disease,but is not the topicality disease,the tumour is the body-wide disease's partial performance.The tumor is one kind of sickness kind,but a non-sickness,its pathogenic factor is very complex.The cause of disease mainly for the external injuries influences attack,the diet injuries,the healthy tendency to owe empty and fine facial expression will being out of balance,the pathogenesis for the stagnation of flow of vital energy blood stasis,the phlegm wet condensation,the painfully hot sun pent up,the internal organs empty damages and so on.The motherland medicine thought that the vitality stasis stagnates is the tumor morbidity basic cause of disease.Vitality being out of balance,the internal combustion engine stagnates strongly fragrant,blood line of impeded,causes the stagnation of flow of vital energy blood stasis,often displays for the blood stasis card.The stasis will tie in the course of time,also will hinder further internal combustion engine's movement,must Cheng xia agglomerate. From the modern oncology angle,the ecchymosis physique's person has the cancer tendency,after the cancer, the malignant transfer rate is obviously high,the recurrence rate is also high,the prognosis is unsatisfactory, the long-enduring blood congeals high the condition and cancer earlier period connection is already established. In addition the tumor occurrence,the development,the shift also with the hemoglutination system exceptionally,the new blood vessel production and so on have the close relation,therefore proposed that in the anticancer treatment treatment strategy,the blood circulation removes extravasted blood big method to select should consider for each treatment principle in the necessity.The modern research indicated that blood circulation removing extravasted blood when the improvement microcycle is unobstructed,also adjusts and the strengthened organism immunologic function,is helpful to tumor suppression,somewhat invigorates the blood to remove extravasted blood Fang Yaogeng to be possible to eliminate the tumour cell directly. This topic is for the purpose of under the Chinese medicine theory instruction discussing the blood stasis the role which acts particularly to cancer pathological change malignant tumor shift.Will visit the traditional Chinese medicine again in the research process to the blood stasis concept,and will treat cancer and the cancer before modern medicine field of vision thorough discussion blood circulation removing extravasted blood the pathological change effect,as well as its ambiguity and the blood vessel will produce relations.From collects and analyzes each doctor of traditional Chinese medicine in the anticancer treatment effect side medicine and the medicine is right,expected that provides another to control the malignant tumor shift and cancer pathological change's treatment choice.MethodThe student from the ancient times medicine and the modern medicine angle through the consult massive literature,has discussed the blood stasis and the malignant tumor relations,both mutual influence,inseparable, therefore proposed that blood circulation removing extravasted blood may pass through in the treatment malignant tumor throughout,and from the approximately 256 short-term Chinese medicine formula medicinal preparation's analysis,confirmed that the blood circulation removes extravasted blood big method to integrate each kind of cancer to govern in the law,and treats big method and uses with other.Fang Ji who analyzes more or less is had the blood circulation removing extravasted blood Chinese medicine ingredient to blend;Has the ancient medical prescription to add and subtract the blood circulation removing extravasted blood medicine, has the blood circulation removing extravasted blood ancient medical prescription,the ancient Chinese medical classics to cut adds again in view of the condition medicine,also has the simple is the side,has the contemporary Chinese medicine newly organized blood circulation removing extravasted blood side.The analysis has prompted several tendencies or the pattern,in the medicine large dose use,the blood was mad that the medicine will widely utilize,near future Fang Jisou the wind medicine universal utilization,especially at terminal cancer.Through analyzes these side medicinal preparation,may be helpful to the understanding blood circulation removing extravasted blood traditional Chinese medicine characteristic,thus is helpful to the clinical utilization.ResultThe traditional medicine thought that the vitality stasis stagnates is the tumor morbidity basic cause of disease,every cancer lump,must the healthy tendency be weak,masculine and feminine elements being out of balance,the vitality function barrier,causes the stagnation of flow of vital energy blood stasis,to gather the phlegm to congeal wet,in the burning abundant and so on mutually the cemented pathological change.But the blood stasis card forms the basic pathology mechanism may summarize is:The stagnation of flow of vital energy blood stasis,the general rule pain,the blood stasis does not form the ecchymosis agglomeration,sends for the tumour,but Cheng Ailiu.The modern medicine discovered that the malignant tumor,the blood coagulation,the new blood vessel produce three relations to be close.The cancer micro environment is the creation in three kind of different cells,then cancer cell,blood vessel cell and host intersititial cell's mutual information conduction.Long-enduring "the blood congeals the condition to confirm high" to the trouble malignant tumor risk.The cancer cell for in the host in vivo multiplication and the shift,must congeal the system with the blood,the antifreeze system and dissolves the fibrin system to coordinate mutually,its aid, promotes the new blood vessel production,thus before the establishment cancer,the blood congeals the vicious circle.The new blood vessel production is the blood coagulation and the malignant tumor shift center link,the hemoglutination system's essential factor like organization factor,the zymoplasm and non-Shui Rongxing the protein may induces the new blood vessel production through the hemoglutination way and the non-hemoglutination way,thus nourishes the cancer cell the growth.In different tumor each stage obvious ecchymosis sign,thus often displayed "blood circulation removing extravasted blood,to treat different diseases with the same method" the method to pass through the tumor treatment beginning to end.Blood circulation removing extravasted blood not only may cause the stasis anti- to wind the arteries to pass again,the ache alleviates,may also eliminate the pathology factor which through removing extravasted blood the cancer lump produces,achieves damps the cancer to shrink the lump,the control tumor development goal,thus relieves the pathology physiology mechanism which the cancer pain occurs.The modern research confirmed that the blood circulation traditional Chinese medicine mostly has presses the class and the antifreeze function,but removes extravasted blood the traditional Chinese medicine mostly to have the anti-hitch to dissolve the hitch function.The tumor molecular biology research indicated that the tumor formation and the shift respectively are the cancer gene with damp the cancer gene,the tumor shift gene and the tumor shift suppressor gene combined action result.The experimental study proof blood circulation removing extravasted blood medicine may affect the tumour cell cancer gene the expression and the DNA synthesis,and through suppresses the blood platelet accumulation to prevent the lump cell detention,to reduce the fibrin content,increases the fibrinolysis,suppresses tumour cell's attack to stick two ways to serve the antifreeze purpose.In addition,adjusts the aspect in the immunity,follows also systematically for the human body immunologic function foundation,is the immunity module's carrier,the vitality unsatisfactory immediate influence immunologic function quality,blood circulation removing extravasted blood may promote the human body immunologic function,the prevention cancer.From each sign,when removes extravasted blood the big method treatment malignant tumor before the blood circulation should consider the cancer the blood stasis important and the priority.The anti-new blood vessel production aspect,the modern research discovery, the blood circulation removing extravasted blood medicine has the following several functions,thus serves the purpose which the anti-tumor new blood vessel produces:①The disturbance blood vessel production factor's release or blocks the blood vessel production factor the function;②Suppresses endothelial cell's multiplication;③Is induced tumor necrosis factor(TNF),to enhance the TNF activeness;④Other non-specificity mechanism.But has the report to execute the blood circulation before clinical to remove extravasted blood big method to treat the cancer and the cancer the pathological change has the ambiguity effect,thus utilizes this big method prevention cancer and the malignant tumor shift compatibility until now was still disputed.The student thinks main and following several spots related:①Lacks the understanding to the symptomless;②The delay governs machine;③The property quality is unclear;④Chooses the medicine prescription to blend the negligence;⑤Envies the medicine and Fang Ji applies drugs the difference to be poor.Above synthesis,so long as has the blood stasis symptom,in principle may select the blood circulation removing extravasted blood medicine,simultaneously can with straighten up the law and use good to;Should when eliminateing the pathogenic factor does not injury positively,straightens up when does not help evilly,with strengthens the patient cellular immunity function the traditional Chinese medicine union use,can obtain a better curative effect.Includes Chinese medicine of anticancer treatment side medicinal preparation the blood circulation removing extravasted blood ingredient,the origin is many,the student from the innumerable books,the weekly, the magazine obtains near for 20 years 256 to have in blood circulation removing extravasted blood the formula medicinal preparation,by the internal organs classification,in the multianalysis side composes,in the induction process,the observation chooses the medicine the nature,the dosage and presents the frequency in each side medicinal preparation classification,refers to certain traditional Chinese medicine pair work to touch again decides the pair frame,obtains the conclusion.①The newly organized proven prescription many take the ancient medical prescription or the ancient Chinese medical classics as a foundation,adds and subtracts the composition to evolve becomes;②In the proven prescription the blood circulation removing extravasted blood traditional Chinese medicine,many are the traditional herbal medicine,minority for modern discovery;③Chooses the side from 256 modern times,the blood circulation removing extravasted blood herbal medicine composition to have certain blending,the medicine turns over to after not to be actually obvious;④The blood circulation removing extravasted blood insect class medicine,is an insect class,is "the flesh and blood feels emotion","the insects to fly away",has uniquely "walks flees" life activeness,therefore the broken stasis relieves congestion the strength internal medicine to externally apply compared to grass class medicine,also has searches for the wind function,uses in the clinical terminal cancer blood stasis serious condition;⑤The sparganium stoloniferum,e the technique is the Chinese medicine anticancer treatment invigorates the blood to remove extravasted blood in Fang Ji the most universal combination;⑥Cancer ache is cancer patient's common later period symptom,the situation one shuts anti-,the stasis for the vein to fill does not pass "not the general rule pain",because the stagnation of flow of vital energy,the blood stasis,the phlegm are often wet,the painfully hot sun causes;⑦From chooses in the side to be possible to observe the Chinese medicine to use the agkistrodon acutus tongue grass the universality which treats at cancer;⑧The Chinese medicine the treat cancer also little extremely to use the metal mineral substance.ConclusionThe blood stasis is many disease extremely common basic pathological changes and the common morbid state,sends to disease tosses and turns turns over to have the material effect.The tumor,from the traditional traditional Chinese medicine theory,is one kind of body-wide disease's partial performance,is one kind of sickness kind,but a non-sickness card,its pathogenic factor is actually complex,between both has,the close relationship complex.The blood stasis may cause the malignant tumor the occurrence,the development,the shift,has the important influence to the prognosis,the tumor may also cause organism hemoglutination function unusuality,has the blood stasis.Therefore,in the anticancer treatment treatment strategy,the blood circulation removes extravasted blood big method to select should consider for each treatment principle in the necessity.Although regarding the blood circulation removes extravasted blood now whether to cause thee tumor shift also to have the dispute,but the student thought that so long as dialectical accurate,will grasp the timeliness,will choose the medicine to be appropriate,the blood circulation removing extravasted blood law treatment malignant tumor will be may obtain the very good curative effect.
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