Flow Phenomenon Study In Tissue Engineering Based On Rapid Prototyping Tecnology

With tissue engineering and rapid prototyping technology development,tissue engineering scaffolds research which based on the rapid prototyping technology is ongoing in depth.The paper discusses numerical analysis method of the two-phase flow properties within the tissue engineering scaffolds. In the solid-liquid two-phase study of cells and nutrition, with CFD software under existing conditions and the need to solve practical problems, against tissue engineering scaffolds based on rapid technology, using Eulerian model to analyze the process of two-phase flow of cells and nutrition in tissue engineering scaffolds. By which obtained the two-phase volume concentration distribution, velocity distribution and the distribution of pressure under a low velocity.Used three different structure of tissue engineering scaffolds for Comparative Study. By which compared the uniformity of the distribution of pressure, cell volume concentration and velocity. By concentration, velocity and pressure analysis, obtained the impact of the fluid flow of the support structure.In contrast to the three structures were found it was very large about flow velocity on the cell concentration. If the velocity is too large, cells can't adsorption, deposited on the wall and easy to be washed away; if the velocity is too small, cells will adsorption and deposited on the wall, which may cause pipeline plug and nutrient solution flow not smooth. This may result in nutrient delivery and waste excretion not smoothing, finally cause the failure of bone formation.The research work is a try of the CFD software used in tissue engineering scaffolds within the solid-liquid two-phase flow about numerical simulation. There is a certain guiding significance for the design optimization of tissue engineering scaffolds and nutrition cells in vitro perfusion technology.