Studies On The Changes Of Hair Follicles Activity And The Localization Of Growth Hormone Receptor In Inner Mongolia Cashmere Goat

The fibre growth of the Inner Mongolia cashmere goat varies periodically according to the season. The activity of the primary and secondary hair follicles appears correspondingly periodic variation. Seasonal factors are known to have important effects on fibre production and quality. Growth Hormone impacts on hair follicles growth. We have investgated the variation of the inner root sheaths in different stages using Sacpic staining method and studied the localisation and expression of the GH receptors in cashmere hair goat follicles using in-situ hybridization analyses. The results showed as follows: (1) The variation of the secondary hair rollicles is viewed a bell shape in diagram. The activity of the secondary hair follicles is highest in autumn and lowest in spring.No apparent differences could be detected in the primary hair follicles after 6-month age. (2) It is demonstrated that the secondary hair follicles ar.e synchronous growth and the primary hair follicles are asynchronous .The results are identical with apparent feature of the fibre growth in the cashmere goat in the different stages. (3) OH receptors are clearly identifiable on the primary and secondary hair follicles. For OH receptors, highest density is observed in the inner and outer root sheaths, demal papilla of both primary and secondary hair follicles on all samples from the different stages. (4)GH receptors appear to have a direct role at both primary and secondary hair follicles growth. Probably, OH promoted the fibre growth.