Study On Antibacterial Properties And Mechanical Properties Of Copper - Bearing Titanium Alloy In

Objective: Through experiments research in vitro， powder metallurgy methodpreparation of titanium-copper alloy of common pathogens of Escherichia coli andStaphylococcus aureus antibacterial properties, and provide theoretical guidance for thedevelopment of alloy antibacterial titanium.Methods: Powder metallurgy method preparation of copper titanium alloy of commonpathogens，the copper content is10wt%.After manual mixing titanium copper powder hotpressing sintering for group A, and the mechanical ball milling titanium copper powder hotpressing sintering for group B, the preparation process parameters are divided into B1~B9group. Mechanical ball milling titanium copper powder hot-pressing sintering for group C, thecopper content is divided into C1~C4group, medical pure titanium as the control group.Choice of Staphylococcus aureus and Escherichia coli as experimental strains. Plate colonycounting method is adopted to improve the evaluation of copper antibacterial properties oftitanium alloy, and through3consecutive polishing processing, detection of copper antibacterialproperties of titanium alloy longer. From B1~B9extract on Staphylococcus aureus andEscherichia coli group has the best antibacterial properties of the specimen, respectively for3h,7h and24h antibacterial rate test. Group C hardness, compressive strength, corrosionresistance and copper ion dissolution test.Results: Compared with medical pure titanium, through three consecutive polishingprocessing, A set of the antibacterial rate of Staphylococcus aureus and Escherichia coli weregreater than99%, show that in group A with stable strong antibacterial function. B1, B5, B6, B8to Staphylococcus aureus antibacterial rate were greater than99%, B2-B4, B7, B9toStaphylococcus aureus antibacterial rate were greater than90%, and B1-B5, B7, B8antibacterial rate of Escherichia. coli were greater than99%, B6, B9antibacterial rate ofEscherichia coli were greater than90%; The B1and B5, B8after three consecutive polishingprocessing for Escherichia. coli and Staphylococcus aureus antibacterial rate were greater than99%, show that B1and B5, B8have stable strong antibacterial effect, including B5theantimicrobial activity of the best. Cultivation of3h,7h,24h after B5for Escherichia coli andStaphylococcus aureus antibacterial rate were35.5%and42.8%respectively,99.0%and91.7%,99.9%and100.0%, can be seen as the extension of incubation time of antimicrobial rate increase gradually. C1for Escherichia coli and Staphylococcus aureus antibacterial rate is lessthan90%, showed that C1does not have antibacterial activity. C2on Staphylococcus aureusand Escherichia coli antibacterial rates were greater than90%, showed that C2has antibacterialeffect. C3and C4on Escherichia coli and Staphylococcus aureus antibacterial rate were greaterthan99%, indicating that C3and C4have strong antibacterial function. Add improved titaniumcopper alloy’s hardness, compressive strength and corrosion resistance, but at the same timereduces the toughness. Increases with increasing concentration of copper ion release withcopper content.Conclusion: Powder metallurgy was prepared to have antibacterial activity of coppertitanium alloy as a whole. Copper content is5wt%of titanium stable antibacterial effects ofcopper alloy, copper added to improve titanium alloy’s hardness, compressive strength andcorrosion resistance. Copper content of10wt%, can obtain the stability of the strongantibacterial activity, B5strong antimicrobial properties of the best.