Research Progress Of Stenosis In Stenosis Of Lower Extremity Arteriosclerosis Obstruction

Lower limb arteriosclerosis occlusion disorder (ASO) is the most common peripheral arterial occlusive disease, is the manifestation of systemic atherosclerosis in lower limb arteries, is part ofa general hardening of the arteries. Extensive disease, mainly involving large and medium-sized arteries, double abdominal aorta and the remote main artery. The disease occurs in males, age more than 45 years of age or older. Along with the social improvement of living standards and the ageing of the population, the incidence of lower limb arteriosclerosis occlusion disorder is on the rise. Easy infection, ulcer and gangrene surgery such as the signs and symptoms of disease, and patients are elderly patients, with metabolic disorders, own the body’s immune function is low, protective feeling. Once the pathogenesis, progression of sharp, difficult to control, to amputation and even death, great impact on the patient’s quality of life.Current treatments include mainly drug treatment of foundation treatment, represented by the classic surgical bypass open surgery and recent development of intracavitary treatment. Traditional vascular flow operation convection novice and outflow conditions of the demand is higher, and this kind of older patients, complications of heart head blood-vessel, the increased risk of bypass surgery, also increase the difficulty to treat. With the development of intracavitary technology and new materials constantly emerging, with minimally invasive, safe and effective in the bellows angioplasty (PTA) has become the treatment of lower limb ischemia effective treatment measures, combined with Stent implantation, can improve the long-term patency rate, on the number of applications has been beyond the trend of the bypass. For lower limb arteriosclerosis occlusion patients brought the Gospel, along with intracavitary treatment increasing number of patients with postoperative complications is becoming more and more attention, especially in the long-term curative effect observation. To better control the occurrence of ISR and development, now the focus from a recent study of Chinese and western medicine nearly five years.At present mainly with vascular endothelial cell damage of formation of the ISR, thrombosis, inflammatory reaction and vascular remodeling mechanism, mechanism of these overlapping each other and influence each other, work together, eventually lead to the occurrence of ISR. also can cause the artery SMC proliferation and mobile middle, resulting in the ISR. Many experimental observation and confirmed by yiqi huoxue clinical data as the primary treatment can reduce the occurrence and development of ISR. And have confirmed that Chinese medicine from the aspects of pharmacological anti-inflammatory, anticoagulation, improving endothelial function, inhibit VSMC proliferation and migration, thus to ISR prevention effect. Clinical data confirm that combine traditional Chinese and western medicine to prevent and control the ISR effect is obviously better than pure western medicine treatment.