| Lower limb arteriosclerosis occlusion disease is common in the elderly peripheral vasculardisease,in recent years,the forming mechanism of lower limb arteriosclerosis occlusion syndrome is being knowned,Treatment with anticoagulation,expansion tube,lipid-lowering therapy and surgery.But the incidence of postoperative restenosis is still high,the effect is not ideal which bring great economic burden to patients.Chinese medicine treatment of lower limb arteriosclerosis occlusion disease has a long history,and have the curative effect.SHU MAI JIAO NANG as one of the common agents for our hospital has repeated authentication and filtering,which improve the patient's clinical symptoms and quality of life,Maintain steady state of blood vessels,prevent further development of disease.ObjectiveBy comparingSHU MAI JIAO NANG and BEI QIAN LIE SU NA in intermittent claudication,or the pain of patients with lower limb arteriosclerosis occlusion syndrome 3 months after treatment with efficient difference before treatment.Evaluation SHU MAI JIAO NANG of lower limb arteriosclerosis occlusion disorder the clinical curative effect of postoperative restenosis,monitor the related physiological,biochemical,microscopic indexes such as physical dynamic change,discuss with lower limb arteriosclerosis occlusion part of the mechanism of the postoperative restenosis,for QI XUE theory in the application of peripheral vascular disease of traditional Chinese medicine to provide material basis and clinical support.MethordAll cases were collected from the Department and ward ofulcers vascular surgery medicine of Bei Jing Chinese Medicine Hospital,Chinese Academy of traditional Chinese Medicinefrom September 2016 to February 2017.According to the implementation plan in 40 patients included in the standard,use the random number comparison research method,divided into treatment group and control group.Foundation treatment group with conventional medical treatment,combined withSHU MAI JIAO NANG,10 g each time,3 times a day,oral BEI QIAN LIE SU NA Simulation piece 40 mg each time,3 times a day.Foundation control group with conventional medical treatment,combined with BEI QIAN LIE SU NA,40 mg each time,3 times a day,oral SHU MAI JIAO NANG Simulation piece 10 g each time,3 times a day.A course of 3 months,in the last 3 months of treatment suffer oxygen partial pressure,laser doppler,ABI curative effect evaluation,and compared with before treatment.Statistics is done by using SPSS20.0 software.Measurement data is done by mean plus orminus standard deviation('x±s)for statistical description.Measurement data of different groups were compared with t test or non parametric test.The count data was compared X2 test.there is statistical difference by p<0.05.In addition,in the treatment of patients was detected before and after treatment the blood routine,routine urine and main biochemical indicators of liver and kidney function.Pay attention to the adverse reactions in the treatment of patients in the process of produce,clear whether the drug side effects.Result1 Baseline analysisTwo groups of patients' age,gender,into the group of ankle brachial than before,percutaneous oxygen partial pressure,laser doppler perfusion,TCM syndrome integral table Compared each item and total score,by t test,nonparametric test,no statistically significant difference were observed in the two groups(p>0.05),the research can be controlled.2Curative effect analysis2.1 The two groups after treatment of blood flow perfusionAfter 1,2,3 months treatment,the treatment group averages are 29.34?33.07?37.42,the control group averages are21.21?21.3 6?23.68,the two groupsof blood flow perfusion are on the rise,Using nonparametric tests,the difference is statistically significant(p<0.05),The treatment group is better than that of control group.2.2The two groups after treatment of left percutaneous oxygenAfter 1,2,3 months treatment,the treatment group averages are 28.71?30.71?37.42,the control group averages are 19.13?24.94?27.51,The two groups after treatment of left percutaneous oxygen are on the rise,Using nonparametric tests,the difference is statistically significant(p<0.05),The treatment group is better than that of control group.2.3 The two groups after treatment of right percutaneous oxygenAfter 1,2,3 months treatment,the treatment group averages are29?31.9?36.52,the control group averages are 26.9?29.4?31.55,The two groups after treatment of right percutaneous oxygen are on the rise,Using nonparametric tests,there are no differences in the treatment of the two groups(p>0.05).2.4 The two groups after treatment of left ABIAfter 1,2,3 months treatment,the treatment group averages are0.77?0.84?0.93,the control group averages are0.61?0.68?0.76,the two groups after treatment of left ABI are on the rise,Using nonparametric tests,the difference is statistically significant(p<0.05),The treatment group is better than that of control group.2.5 The two groups after treatment of right ABIAfter 1,2,3 months treatment,the treatment group averages are0.82?0.93?1,the control group averages are0.75?0.69?0.77,Using nonparametric tests,the difference in 2and3 months is statistically significant(p<0.05),The treatment group is better than that of control group.there are no differences in the treatment of the two groups in 1 month(p>0.05).2.6 The two groups of blood flow perfusion between treatmentAfter 1,2,3 months treatment,the treatment group averages are29.34± 10.99.33.07 ±10.24?37.42 ± 9.52,using two paired sample t test,the difference is statistically significant(p<0.05),the control group averages are21.21 ± 11.11?21.36± 10.22?23.68 ±10.07,using two paired sample t test,the difference is statistically significant(p<0.05).2.7 The two groups of TCM syndrome scorethe treatment group is better than that in the treatment of intermittent claudication,skin temperature,ABI,percutaneous oxygen aspects of the control group,Using nonparametric tests,the difference in 2and3 months is statistically significant(p<0.05),there are no differences in the treatment of the two groups in pain,numb aspects(p>0.05).ConclusionSHU MAI JIAO NANG treatment to lower limb arteriosclerosis occlusion disorder postoperative restenosis is superior to BEI QIAN LIE SU NA,SHU MAI JIAO NANG treatment can improve the patient's clinical symptoms and quality of life,maintain steady state of blood vessels. |
PDF Full Text Request