Clinical Study On Treatment Of Posterior Deep Venous Thrombosis Syndrome With Yiqi Huoxue Qushi Tongluo Method

Objective:Villalta score was used for diagnosis and evaluation of the post-thrombotic syndrome.Through the observation of symptoms, signs, circumference difference of above knee, circumference difference of below knee, venous outflow, PT, APTT, FIB levels improvement before and after treatment,and with the western medicine of Aescuven forte compared to evaluation of clinical curative effect of supplementing qi and activating blood circulation and eliminating dampness and dredging collaterals method mainly by the modified buyanghuanwu decoction on the post-thrombotic syndrome.Then, explore the effect of supplementing qi and activating blood circulation and eliminating dampness and dredging collaterals method in lower extremity venous diseases, to provide new ideas and methods for the future of traditional Chinese medicine in the treatment of PTS.Methods:Using randomized method, will meet the inclusion criteria for the study of post-thrombotic syndrome patients 72 cases, divided into the treatment group of 36 cases and 36 cases in the control group of Western Medicine.In the conventional treatment based on the same,treatment group were treated with supplementing qi and activating blood circulation and eliminating dampness and dredging collaterals traditional Chinese medicine mainly by the modified buyanghuanwu decoction treatment, the control group were treated with oral Aescuven forte.After 1 courses of treatment (30 days) after treatment, compared two groups of patients with changes of Villalta score, symptom score, symptom score, circumference difference of above knee, circumference difference of below knee venous return flow, PT, APTT, FIB levels, and compare with before treatment.Statistical analysis of data using SPSS 17.0 software, the observation index by using the t test or non parametric test, count data using x2 test, evaluate the clinical efficacy of two different methods in the treatment of post-thrombotic syndrome.Results:After 1 courses of treatment, the total effective rate of treatment group 91.66%, control group total effectiveness 77.78%, the treatment group was significantly higher than that of the control group (P<0.05).In the Villalta score, symptom score, symptom score, after treatment, Chinese medicine treatment group and Western medicine control group were significantly improved compared with before treatment. Comparison between the two groups, there was significant difference. Comparison of efficiency based on Villalta score, treatment group was significantly better than the control group. Description of Chinese medicine and Western medicine of Aescuven forte in the improvement of PTS symptoms and signs have the curative effect, but the traditional Chinese medicine has more advantages.In circumference difference of above knee, circumference difference of below knee, after treatment, Chinese medicine treatment group and Western medicine control group before treatment were decreased. But the two groups are compared, there was no significant difference. Description of Chinese medicine and Western medicine of Aescuven forte in both reduce limb swelling effect, but the traditional Chinese medicine in this aspect does not reflect the more obvious advantages.In the venous outflow, after treatment, two groups of outflow volume than before treatment were improved. Chinese medicine treatment group and Western medicine control group were compared, there was significant difference. Description of Chinese medicine and Western medicine of Aescuven forte can improve lower extremity venous return, but the efficacy of traditional Chinese medicine is more clear.In the coagulation of blood, after treatment, Chinese medicine treatment group the level of APTT was extended, the level of FIB was decreased, and there was statistical significance, although the level of PT was increased, but no significant difference. In the western medicine control group PT, APTT, FIB levels, compared with before treatment was statistically significant. Traditional Chinese medicine treatment group and Western medicine control group were compared, differences in PT, APTT, FIB levels. The traditional Chinese medicine can prolong APTT and reduce FIB to improve high blood coagulation state, but the effect is not obvious to improve the level of PT. While the western medicine of Aescuven forte in improving blood coagulation did not reflect the effect.Conclusion:Supplementing qi and activating blood circulation and eliminating dampness and dredging collaterals method mainly by the modified buyanghuanwu decoction has significant effect on PTS, the total efficiency is better than western medicine group. Yiqi Huoxue Qushi Tongluo method in the treatment of venous diseases of lower extremity, can improve the patient’s symptoms and signs, improve the venous reflux, but also to ease the blood hypercoagulable state, the prevention of recurrent thrombosis can also play a role. No obvious adverse reaction in the medication process. There are obvious advantages in comparison with the western medicine of Aescuven forte. Syndrome differentiation and treatment of Chinese medicine characteristics in relieve the pain of patients, improve the quality of life of patients has bright prospects, but also provide new evidence for the treatment of PTS.