Correlation Between TCM Dialectical Classification And Child - Pugh Classification And Related Indexes In Cirrhosis Of Liver

Purpose: This paper probes into the Traditional Chinese Medicine (TCM)syndromes of liver cirrhosis, and analyzes its connection with Chine-Pughclassification, providing objective basis for the TCM dialectical treatmentof liver cirrhosis.Method: The research is conducted over491cases meeting the criteria,recording the related indicator including the patients’ gender, age,pathogenesis, symptoms, signs, liver function, kidney function, bloodcoagulation, blood, plasma, Child-Pugh classification and complications, andanalyzes these statistics with SPSS17.0software. This research reviews andanalyzes the cases treated in department of infectious diseases andgastroenterology ward for nearly a decade in the hospital of Liaoning Universityof Traditional Chinese Medicine, to investigate the connection between TCMdialectical classification and objective indicator.Results: The491liver cirrhosis cases can be divided into five types:87cases caused by damp-heat syndrome, accounting17.71%;141cases caused bystagnation of liver Qi, accounting28.72%;42cases due to blood stasis,accounting8.55%;129cases due to damp abundance caused by splenic asthenia,accounting26.27%;36cases of spleen and kidney Yang deficiency, accounting7.33%; and56cases of Liver and kidney Yin deficiency, accounting11.41%. Asto the Child-Pugh classification of the above cases, cases due to stagnationof liver Qi mainly centered in grade B. Endoretention of damp heat cases, whichmostly caused by excessive pathogen, while the Healthy atmosphere has alreadybeen damaged, consists of mainly grade B, and a few of cases of grade C, andgrade C are also not rare in such cases. The spleen and kidney Yang deficiencyand Liver and kidney Yin deficiency are always found in the advanced cirrhosis, combined with the symptoms of damp abundance caused by splenic asthenia, takingup mainly grade C and a few of grade B. In liver cirrhosis, blood stasis isusually combined with other pathogenesis. In the Child-Pugh classification,the objective indices include bilirubin (TB), albumin (ALB) and prothrombintime (PT). In the research studying the connection between above index and livercirrhosis TCM syndrome, TB is found high in cases of blood stasis andendoretention of damp heat, ALB level sequence is stagnation of liver Qi> bloodstasis> liver and kidney Yin deficiency>spleen and kidney Yang deficiency>endoretention of damp heat> damp abundance caused by splenic asthenia; and PTlevel sequence is endoretention of damp heat> blood stasis> liver and kidneyYin deficiency> damp abundance caused by splenic asthenia> stagnation of liverQi> spleen and kidney Yang deficiency.Conclusion:1. The case group mainly comprises syndromes of stagnation ofliver Qi and damp abundance caused by splenic asthenia, reflecting thepathogenesis of stagnation of liver qi and spleen deficiency runing throughall the stages of liver cirrhosis. Few cases are merely caused by blood stasis,which usually combined with other causes in the syndromes. Liver and kidneyYin deficiency and spleen and kidney Yang deficiency are mostly seen in advancedcirrhosis, combining symptoms of damp abundance caused by splenic asthenia.2. The core of cirrhosis pathogenesis evolution is stagnation of liver qi andspleen deficiency. Extravasated blood, which is the result of past pathogenesisevolution, and which also results in a new phases of pathogenesis evolution,should be taken into account in the treatment.3. Child-Pugh turns from grade A to grade C along with the development of thedisease, while in TCM syndromes, stagnation of liver Qi gradually develops toliver kidney Yin deficiency and spleen and kidney Yang deficiency.