Experimental Study And Clinical Observation Of Self - Made Huatanzhike Decoction On Cough In Children With Phlegm And Obstructing Lung

Purpose：To observe cough and Removing sputum on mice by HuaTanZhiKe soup；to study the therapeutic effect and Adverse reactions On children patients incough belonged to TanShiYongFei,And to explore Mechanism of children patientsin cough.Material and method：On the experimental study：The effects of differentdose of HuaTanZhiKe soup, Two Chen pill and the blank group, to investigate thecough, Removing sputum on mice and mice expectorant effect of acute and long-termtoxicity.on the clinical study:Take a random method, divided into the treatmentgroup and the control group, the treatment group for HuaTanZhiKe soup group,control group of Two Chen pills group.Results:On the experimental study：in cough,The incubation period can be prolonged coughin mice, reducing the number of cough in mice, there are significant differencesbetween the control group and the blank（P<0.05). In Removing sputum,increasedsignificantly the amount of phenol red in mice shedding, and the blank controlgroup have obvious difference（P﹤0.01).In long-term and acute toxicity:Organswere normal histological changes.On the clinical study:After treatment, The total effective rate of treatmentgroup was88%, the blank control group total effectiveness is80%. The treatmentgroup in improving symptoms and signs and the main symptoms disappear time werebetter than the control group.Conclusion:HuaTanZhiKe Soup(1/2times,1times,2times,4times) has antitussive andexpectorant effects，also not appear acute and long-term toxicity reaction, HuaTanZhiKe Soup has good curative effect on children patients in cough belongedto TanShiYongFei.