Monitoring And Analysis Of Antibody Levels Of Avian Influenza H5 Subtype In Fowl In Xi'an City

Highly pathogenic avian influenza(HPAI)is a highly contagious viral disease affecting infect domestic poultry and wild birds.It is classified as A class contagious animal disease by OIE.Clinic sign of AI include subclinical infections,respiratory disease,or drops in egg production,high mortality rates et.al.Avian influenza are divided in two groups based on their ability to cause disease(pathogenicity).Highly pathogenic avian influenza(HPAI),low pathogenic avian influenza(LPAI).High pathogenic influenza was first found in Italy in 1878 and distributed worldwide.The clicnic of HAPI include cyanosis and hemorrhage of comb and wattle,edema of the head,ocular discharges,dispnea.The specific clinic signs are hemorrhage of foot and shank,edema of hypodemic tissue hemorrhage and necrosis or ulcer of ocular conjunctiva and alimentary canal.Highly pathogenic avian influenza(HPAI) spreads rapidly,may cause serious disease and result in high mortality rates and devastate of poultry industry.It has focused the importance of public health risk from human infection case of Hong Kong in 1997.Forcible vaccination of present poultry is important measure to prevent the disease and be executed in China from 2004.In the situation of vaccinate present poultry all country,There are many correlative factors(such as the virus's antigenic drift and antigenic shift,the migrating bird and water fowl play the important role in spread the diseases,etc.),It is necessary to monitor and analyse the antibody titers in poultry immunized with inactivated H₅ subtypes oil-emulsion vaccine,and that will be provide beneficial reference for later prevention and control work.The High pathogenic avian influenza outbreak of Chang'an district in 2004 was eliminated quickly with efficient measures.From 2004 activity for immunity for HAPI was carried out during the spring and autumn in xi'an city.For understanding the antibody creation situation and antibody titers distribution of poultry after the concentration immunity,The writer carries monitored antibody of chickens induced by inactivated vaccine in Xian,The blood was collected with 2626 portions from Chang-an district;Zhou-zhi county;Gao-ling county;et al.The ration of antibody qualified reached 84.3%through hemagglutination test and hemagglutination inhibition test detecting. The immunity state of collection samples were classification analyzed.The results indicated that the level of bird flu antibody kept on stable 3～9 weeks after immunization and began decreased after 10 weeks;the lever of avian flu antibody was better if immunity 2～3 times.