Clinical And Experimental Study Of Fu Fang Cang Er Chong Ointment For Promoting Healing Of Wound After Operation On Anorectal Diseases

Objective: To observe the clinical effect of Fu Fang cang Erchong Ointment on promoting the healing of wound after the operation on anorectal diseases.Methods: We smeared the ointment directly on the normal rabbit's skin to observe the stimulation and hypersensitivity in the experimental study. We oborved the clinical efficiency of Fu Fang Cang Erchong Ointment on the wound of anorectal diseases.Results: In experimental study, we found that FFCECO had not any stimulation and hypersensitivity. so we used it for Promoting the healing of wound after operation the hemorrhoid. Fifty patients underwent the operation. They were randomly divided into 2 groups (25 cases each), Group I was treated with FFCECO on their wounds while group Ⅱwith Kang Fu Xing. The result showed that group I and group Ⅱwere similar in the wound edema, exudation of the wound surface. The group I was better Group Ⅱ in the grouth of skin.The TNF-αcontents in the granulation tissues of two groups were becoming decremental after the operation. In each group The TNF-α contents on the 5th day after surgical wound had significant differences on the 7th day(P<0.01). The Fn contents in the granulation tissues of two groups were increased between the 5th day and the 7th day. The Fn contents had significant changes in each group,but between group Ⅰ and groupⅡ the TNF-α contents on the 5th day and the 7th day had no significant (P>0.05) the Fn contents on the 5th day and the 7th day had significant (P<0.01) differences . The time of healing of wound had no significant (P>0.05) differences between the group I and group Ⅱ These results Suggested that FFCECO and KFX had a similar clinical effect in the promoting Healing of wound after operation on the anorectal diseases.Conclutions: These findings suggest that the effect of The effect of FFCECO and KFX was similar. The mechanisms of FFCECO were improving microcircutation, promoting phagocyte effusion and hyperplasia and regulating immune function of human body, so as to dispel pain. Also the FFCECO have the function of controling the infection, promoting the hyperplasia granulation tissues and increasing the healing of wounds.