| With rising incidence rate of diabetes year after year, diabetic retinopathy has become one of the major eye - diseases that may cause blindness among the adults. How to reduce the cases of blindness caused by DR has become the urgent task for ophthalmological research field. As the treatment for DR, photoco-agulation has been proved effective by clinic. It has been indicated that the rate of blindness of the treatment group was 50% lower than the non - treatment group. However as a distractive method, it is certain that photocoagulation will make some effect on the normal structure and function of retina and consequently cause many side - effects, even cause the lose of eyesight forever. Therefore, in clinical practice, it is worthy to study how to adjust the laser parameter reasonably , how to determinant the level of the laser reaction correctly and how to a-chieve the good effect and reduce the rate of syndrome at the same time. We will treat 20 cases of DR patients with Argon laser of low energy and small spot and statistically analyze the results and the one of DR patients who had been treated with Argon laser of high energy and big spot, and observe the effect.ObjectiveTo observe the effect of low energy and small spot Argon panretinal photo-coagulation on DR and the clinical findings of laser damage to retina after the treatment, and to investigate whether the treatment of low energy and small spot Argon panretinal photocoagulation can achieve the good effect and reduce the side - effects at the same time.Methods20 eyes of 13 DR patients who underwent Argon PRP in 2003 were chosen into A group and 20 eyes of 14 DR patients who underwent Argon PRP from 1998 to 2001 were chosen into B group. All the cases were diagnosed as HI ~ IV grade DR according to the current standard of DR type and stage in China. The refracting media of all the eyes were clear, no patient had other retina diseases and no previous photocoagulation and surgery had been carried out on any of these patients. The general exams including blood pressure, blood sugar , HbAlc, blood fat and detailed ophthalmologist exams such as naked eyesight , optometry, tonometry, B - scan, biomicroscopy of the anterior eye segment , visual field , ERG, FFA and color photo of fundus were carried out on every patient. Standard Argon PRP for every eye was divided into 4 times, once a week. The eyes of A group were treated by low energy and small spot laser and the eyes of B group were treated by high energy and big spot laser. Three months after the treatment , naked eyesight , the best corrective eyesight, visual field ,ERG, FFA and color photo of fundus were examined. The results of the two groups were compared and statistically analyzed.Results1. There was no significant difference between all the preoperative results of the two groups( p >0.05) .2. Three months postoperatively in A group the eyesight of 3 eyes (15% ) were improved; the eyesight of 13 eyes (65% )were unchanged; the eyesight of 4 eyes were declined. In B group the eyesight of 4 eyes(20% ) were improved; the eyesight of 12 eyes(60% ) were unchanged; the eyesight of 4 eyes(20% ) were declined. There was no significant difference compared between the two groups (p >0.05).3. Three months postoperatively 15 eyes (75%) of A group and 14 eyes (70%) of B group have been proved effective by FFA, 5 eyes (25%) of Agroup and 6 eyes(30% ) of B group have been proved ineffective. There was no significant difference compared between the two groups (p >0. 05).4. Preoperatively the light sensitivity of center 30 of the A group and B group were 30.4 2. 9dB ,28. 6 3. 4dBseparately, and that of peripheral 60 were25.0 3.1dB, 24. 3 2. 2dB separately. Three months postoperatively, the light sensitivity of center 30 of the A group and B group were28.9 2. 8dB, 26. 2 3. 9dB separately, and that of peripheral 60 were24.1 3. 3dB, 22.5 2.3dB separately. There was significant difference compared the differences of pre - operate and post - operate between the two...
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