The Experimental Study Of The Effect Of Electro Acupuncture To The Nervous Plasticity In Rats After Acute Cerebral Infarction

Purpose: To investigate the effect of electro acupuncture to the structure basis of nervous plasticity and the recovery mechanism after acute cerebral infarction. Methods: A rat model of focal cerebral is chemia was made by filament occlusion of the middle cerebral artery. The effect of electro acupuncture in Qian san Li and Hou san Li to a rate's change in infarction tissue, necrosis of neuron and vessel, synapse microtubule associated protein 2(MAP-2),and synaptophysin wore observed by electron scope, light scope ,and immunohistology staining . Results: Electro acupuncture could improve histopathologic indices, increase the number of synapse, and promote the recover of synapse's structure, increase the expression of the SYN and map-2 .Conclusion: Electro acupuncture can produce a marked protecting effect on the brain in Wistar rats focal cerebral ischemia, regulate the plasticity of cerebral neuron.