| Objective: To observe the effect of the periodical therapy of Chinese medicine combined with clomiphene /bromocriptine on patients with anovulatory infertility and to explore the mechanism of this treatment from the view of Chinese traditional medicine.Method: 52 cases of anovulatory infertility were divided into two treatment groups:GroupA,(n=25) treated by clomiphene/ bromocriptine. GroupB, (n=27) by Tiaoj ingzhuyun decoction and clomiphene/bromocriptine, respectively. After treatment, the serum level of progesterone was measured in the 21- 23th day of menstrual cycle. With transvaginal sonography the follicular development and periovulatory endometrial thickness were monitored. The effects of treatment were evaluated by pregent rate, ovulatory rate , periovulatory endometrial thickness,the cervical mucus scores, basal body temperature and the serum level of P.Results: serum level of P in group B was higher than that in group A. The other indices in group B is better than those in group A. The efficiency of group B is superior to group A.Conclusion: The periodic therapy of Chinese medcine combined with clomifene/bromocriptine is an effective recipe in ovulation induction. The effect may be achieve by this treatment through regulating the function of hypothalamus -pituitary - ovary axis and the endocrinal enviroment in the patients with anovulatory infertility.
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