The Clinical And Experimental Researches On Diabetic Gastroparesis Treated With Electric Acupuncture

Diabetic gastroparesis is one of the chronic complications of diabetes mellitus. Hypotonia of the sinus ventriculi and emptying delay is the major pathology changes of the DGP. Hypomotility and step down leads to food stasis in sinus ventriculi. The symptoms of upper gastrointestinal reside in DGP and The symptoms threatens the patient' s living quality severely. DGP effects diabetes to control the blood glucose. Out of control blood glucose is the fundamental reason of severe complication. Researchs indicate that needling some acupoints can adjust gastric motility and gastric secretion in two-way optimum. We assumed that therapeutic effect is satisfactory to acupuncture on diabetic with gastroparesis. The objective of this investigation is to get the message from therapeutic effect of electric acupuncture on DGP.To comprehend the effects of the blood glucose after changed gastric emptying. To conclude the mechanism of action of electric acupuncture. I desire that this investigation can provoke clinician to pay attention to DGP.The history of DGP is up of fifty years, nowadays. Medical science make advancement in physiology pathology and immunology. Diagnostic method and indicatrix is unceasing consummate. The detection rate is 46.3%~62% in diabetic in different diagnostic method. The etiopathogenisis and pathogenesy not yet completely identify. Most scholar thinks it important of hyperglycemia and autonomic neuropathy.DGP belongs to the syndrome of feeling fullness and distension in the upper abdomen of traditional Chinese medicine. The pathogenesis is long time of diabetes leads sputum, moist, stagnant blood to block middle energizer. DGP results in dys-splenism and stomach-QI being unable to descend normally. We must deal with basal illness and assist the transportation and transformation of middle energizer. Splenism rises clear QI and stomach descends the turbid.After summarizing the general caves which is good for syndrome of feeling fullness and distension in the upper abdomen, we sieve middle epigastrium, foot three li, stomach shu, lefe beam gate, tianshu. Used electric acupuncture. The control group oral mosapride. To investigate the clinical effect on DGP with electric acupuncture. The results as follow:60 in patients with DGP whose gastric emptying rate is under 52.8%accompany with clinical symptom were randomed allocation to electric acupuncture group and control group.30 patients in each group. The total effective rate of syndrome of feeling fullness and distension in the upper abdomen and gastric emptying rat is 60. 87% and 76. 94% in electric acupuncture group and 38. 15% and 74. 13% in control group. The concentration of motiiin in both groups is degression post-treatment (P<0.01) . The concentration ratio of motiiin between electric acupuncture group and control group isn' t statistically significant in post-treatment(P>0. 05). Electric acupuncture degraded the gastrin (P<0. 05), and mosapride can cut the gastrin down also but isn' t statistically significant(/>>0.05). Difference of two groups isn' t statistically significant(P> 0.05). Fasting blood glucose and microdosis blood glucose 2 hours post meal decrease obviously after treatment(/*<0. Olor P<0. 05). Difference of two groups isn' t statistically significant(P>0. 05). We concluded that electric acupuncture is better for improving the clinical symptom and accelerating gastric emptying of DGP. The changes of motiiin and gastrin during therapy maybe is one of the mechanism of the treatment with electric acupuncture.In our empirical study,we used streptozocin to produce the insulin-dependent diabetes mellitus rats. 30 rats were randomed allocation to electric acupuncture group and control group 10 weeks after the mode established .We set up 15 vacant rats as observation group. We needling the electric acupuncture group in middle epigastrium, stomach shu, post-foot three li. Electric acupuncture with continuous wave. The control group and the observation group hadn' t given any treatment. Blood glucose in electric acupuncture group and control group is higher, than in observation group (P <0. 01). Blood glucose in electric acupuncture is decreased after treatment comparing with same group 10 weeks after the mode establishedC/^O. 05). Blood glucose in electric acupuncture group and control group isn' t statistically significant after treatment(P>0. 05). Stomach intestine facilitation ratio in control group is lower than in observation group and electric acupuncture group(P<0. 01). The concentration of motiiin in control group is higher than in electric acupuncture group and observation group ( P< 0.05 ) . The concentration of gastrin in control group is higher than in electric acupuncture group and observation group but isn' t statistically significant(P> 0.05). We concluded that the insulin-dependent diabetes mellitus rats exist gastric emptying delay hypermotilinemia and electric acupuncture accelerates gastric emptying of rats and degrades motiiin. Probably electric acupuncture can depress the blood glucose concentration by accelerating gastric emptying.Electric acupuncture can accelerate gastric emptying and is better for improving the clinical symptom of DGP. Electric acupuncture also can lower content of motiiin and gastrin. Accelerating gastric emptying is helpful to control the blood glucose of diabetic. Acupoint with electric stimulation at gastric region accelerates gastric emptying and improved the efficacy of...