Review Ilexonin A The Myocardial Preservation Offor Necrosis Myocardial Of AMI And The Ilwxonin A Ingtervention Preservation Of Cell Factor Heighten In AMI Version

Objective: Through rabbit AMI version, to review the myocardial preservation of ilexonin A for necrosis myocardial of AMI and review the Ilwxonin A ingtervention preservation of cell factor heighten in AMI. Material and Method: 1) laboratory animal and group: 18 albino rabbits weight between 2.5-3.0kg masculinity trabant divla two groups, each group 9 rabbits (1) operation control group (2) ilexonin A group. Each group was narcotized routinely, turn-on the chest and coronary artery ligation. The Ilexonin A group: before being operation the rabbits were intravenous injection 5% Ilexonin A though the ear lip vein. 2) Manufacture of animal model: after weighting the rabbit was intravenous anesthetized by 1.5% carbrital 30mg/kg. To be fixed backlying on the operation table, in the sterilitas qualification porch belong midsternal line longitudinally cut cutaneous (form angle of stremun to appendix ensiformis), turn-on the chest bone belong midline of chest bone, the length is about third to fifth cervical rib and expose heart raising arcula cordis carefully and turn-on the arcula cordis To be sutured arcula cordis on the opened muscles of thorax. To form a hannock of arcula cordis, it is thus evident that cardiac vein is concomitant anterior descending cornary that is courser under cardiac vein. LAD is under the lamellar cardiac muscle ,using cardiac vein like marker hypodesmus its supra-juncture 1/3. 3) Data acquisition: Record ECG of lead â… , â…¡, â…¢, AVR, and before operation and after operation get blood 5ml from chambers heart, centrifugal separation blood cell and blood serum. Take those cryopreservation results: confer control group and ilexonin A group after turn-on chest deligation anterior descending branch memorize how long the rabbit is dead. control group's mean survival time is 4.21h 3 rabbits survival time exceed 6h and in the ilexonin A group there are 7 rabbits survival time exceed 6h; compare control group and ilexonin group ECG S-T piece instant 1hour 2hour time of two group Sig are 0.002, 0.015, 0.005 signficant differences were observed between the 2 groups compare control group and ilexonin group CRP level of two group.time is before operation and after operation 4h control group before operation and ilexonin group before operation: p=0.313 signficant differences were not observed between the 2 groups. Contral group before operation and contral group after operation; ilexonin group before operation and ilexonin group after operation; contral group after operation and ilexonin group after operation: P<0.001. signficant differences were observed between the 2 groups. compare control group and ilexonin groupIL-6 level of two group. time is before operation and after operation 4h control group before operation and ilexonin group before operation: p=0.509 signficant differences were not observed between the 2 groups. Contral group before operation and contral group after operation; ilexonin group before operation and ilexonin group after operation; contral group after operation and ilexonin group after operation:...