The Diagnostic Value And Quantitative Assessment Of Left Ventricular Systolic Function In Patients With Coronary Heart Disease By Adenosine Stress Echocardiography

Objective: The aims of this study were to evaluate the diagnostic value of Adenosine Stress Echocardiography and quantitative assessment of left ventricular systolic function by Color Kinesis and Tissue Doppler imaging in patients with coronary heart disease,and investigate the action.Material and Metheds: Adenosine Stress Echocardiography was performed in 56patients with suspected coronary heart disease before coronary angiography within oneweek. According to the 16-segments model formulated by American Society ofEchocardiography,the left ventricle was divided into 16 segments and we observed thewall motion and contraction for judging the location and regions of segments withRWMA,and the segments systolic function was examined by CK and PW-TDI at restand stress time. The contents mainly studied: (1)CK: Color kinesis demention (SEM ),Color kinesis velocite (Vsem);(2)PW-TDI: peak systolic velocite of subendocardialmyocardium of segments(Wave Sa).Results: The total sensitivity and specificity and Adenosine StressEchocardiography was 85.3% and 71.4%,the sensitivity for detection of myocardialischemia in one,two and three-vessel CAD sub-groups were 84.6%,83.3% and 100%respectively,the sensitivity for detection of single vessel CAD in LAD and RCA(90.9%,88.9%) were higher than that in LCX(66.7%),deduced the certain coronary arterystenosis by correlation of RWMA. Side effects due to adenosine infusion were alwaysminimal and well tolerated by the patients and disappeared with in seconds aftertermination of infusion. During Adenosine Stress Echocardiography the sensitivity andspecificity of color kinesis is 91.2% and 76.2%,higher than those of 2-DE. Afteradenosine infusion,the inward motion distance of normal area increased significantly ,inreverse ,that of the ischemia area decreased significantly. PW-TDI combined withAdenosine Stress Echocardiography the Vs of normal area increased significantly, that ofthe ischemia area decreased significantly. Conclusion: Adenosine Stress Echocardiography was a safe ,convenient and accuratemethod to diagnose CAD.During Adenosine Stress Echocardiography the sensitivity andaccuracy of color kinesis were higher than those of 2-DE ,the quantitative parameter SEMhas great value in clinical application. PW-TDI combined with Adenosine StressEchocardiography can correctly evaluate left ventricular regional systolic function of longaxis and detect ischemic myocardium. Vs is the main parameter.