Studies On The Chemical Components In Bioactive Part And HPLC Fingerprint Of The Tibetan Medicinal Substance Herpetospermum Seed

Herpetospermum seed is the dried ripe seed of Herpetos permum Caudigerum Wall..As a commonly used Tibetan medicinal substance, it is recorded in Drug Standards-Tibetan Medicinal Substances (Vol. 1) ,issued by The Ministry of Health. Herpetospermum seed is bitter in taste and cold in nature. Its actions include clearing heat from fuorgans (e. g.gallbladder), detoxifying, purging the fire, and aiding the digestion. It is indicated for liver heat syndrome ,hepatitis A,etc.The prediction test of its chemical components shows that it contains alkaloids,amino acids, proteins,polypeptides,fatty oil, tannins,phenols, co-umarins, lignans, triterpenes, steroids,saponins,etc. Bolengsu compound was isolated by Yuan Hailong, benzofuran compounds (such as Herpetal and Herpetoriol) and lignans (such as Herpetrione, Herpetetradione, Herpepentol,Herpetol, Herpetetrone) were isolated from this herb by Kaouadji Mourad et al. No pharmacological studies on Herpetospermum seed were ever report. The quality control index of this herb noly include characteristic description, micro-characteristic description and qualitative description of alkaloids in Drug Standards-Tibetan Medicinal Substances (Vol.1)Studying on the chemical constituents from active part for liver diseases of the Tibetan medicinal substance herpeto- spermum seed,three compounds were isolated from it. , By means of UV,IR,MS , ¹H-NMR,¹³C-NMR, they were identified as ( I )herpetfluoren one,...