Study Of Ultrasonic Strain Rate Imaging And Dobutamine Stress Echocardiography In Detecting Ischemic Myocardium

Objective: To assess the value in detecting ischemic myocardium by ultrasonic strain rate imaging combined with dobutamine stress echocardiography (DSE). Methods: Fifty subjects with suspected coronary artery disease (CAD) underwent DSE and coronary angiography. According to the results of coronary angiography, all subjects were divided into two groups: CAD group and normal group. The systolic peak strain rate (SR) were respectively measured on middle segment of the left ventricular anterior wall and lateral wall from apical three chamber and two chamber in rest and every stress stage, and their results were compared with those from coronary angiography. Results: In normal group, the systolic peak SR values increased while dobutamine dose rise (P < 0.05) , reaching the highest values at the peak dose of dobutamine. In CAD group, SR values increased at low dose, and significantly reduced (P < 0.05 ) at peak dose 40μg/(kg·min).The sensitivity and specificity of SRI with DSE for detecting ischemic myocardium were 90% and 91.7%, respectively. Conclusions: SR combined with DSE will increase the prevalence of ischemic myocardium. In 40μg/(kg·min) dose, SR was the most sensitive to detect the ischemic myocardium.