| Background: The problems induced by the growing prevalence of increased obesity and hyperlipdemia have raised more significant concerns. It has been demonstrated obesity and hyperlipdemia are the risk factors that are associated with heart disease, hypertension, stroke and so on. Recently, some studies have documented obesity and hyperlipdemia, which may be the risk factors, are associated with periodontitis. Objective: The purpose of this study is to identify the relationship between obesity, hyperlipdemia and periodontitis, with investigation on the obesity, levels of hyperlipdemia and periodontal conditions about officeholders in Wuhan city. Material and methods: The study sample are coming from officeholders in Wuhan city, which are classified as the districts of Hanyang, Hankou, Wuchang, sampled as the rule of random and all group. The final study populations are 458 after examined by included and excluded rules. Cross-sectional survey was carried out. The methods of investigation include: Questionnaire associated with general conditions; periodontal situations were examined by two postgraduates of clinical pattern of the periodontal department of the Stomatology Hospital of Wuhan University. The details of examination were standardized; the difference has no statistical significance. The data of physical condition were acquired from physical examination. Body mass index (BMI) was used as measure of obesity, which is computed from weight in kilograms divided by square height in meters." ≥ 28 kg/m2 is defined as obesity. The level of serum lipid is accessed by triglyceride (TG) and total-cholesterol (TC). TC is classified as sicken group and healthy group. < 5.7mmol/l is defined as healthy group; ≥ 5.7mmol/l is defined as sicken group. TG is classified as sicken group and healthy group. < 1.70mmol/l is defined as healthy group; ≥ 1.70mmol/l is defined as sicken group. Withthe systemic software pack of managing dental data manufactured with Ruisi Software Company of Wuhan University, the data were recorded and managed. The results were analyzed with SPSS 11.5 software pack. In simple risk factor analysis, all variables were tested with non-parametric method (x 2-test) in order to get risk factors(P<0.05). Logistic regression analysis was run with all factors and it was done again after age was adjusted (classified as working group and retired group) in order to discuss the relationship between obesity, hyperlipdemia and periodontitis.Results: The positive correlation of triglyceride was found in simple risk factor analysis, but not in the last result of. logistic regression analysis; and total-cholesterol, obesity in the last result. Logistic regression analysis in all group, total-cholesterol (OR=2.663, CI 1.547~4.586) is the risk factor.The group was divided into two groups by age: 30~ (working group); 60~79 (retired group) . Contrasting to normal weight group, the effects on periodontitis of underweight group, overweight group, and obesity group have no obvious difference. (The inefficient value "OR=l"was included in all confidence interval.) Logistic regression analysis in working group, overweight (OR=1.840, CI 1.040-3.254), obesity ( OR = 2.972, CI 1.155—7.415) and total-cholesterol (OR = 2.758, CI:1.452~5.239) are the risk factors. Logistic regression analysis in retired group, the relationship between obesity (OR = 0.090, CI 0.019~ 0.427) and periodontitis reduced; total-cholesterol ( OR = 5.506, CI 1.617~ 18.747) is the risk factor.Conclusion: In this study, total-cholesterol and obesity are associated with periodontitis. Obesity has different effect on different age group, obvious effect on the young-adult group. From 30 to 60 years old, obesity is the risk factor. Total-cholesterol is the risk factor, whose role is getting important with the growth of age; triglyceride has no obvious effect on the periodontitis.
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