Clinical Analysis Of 102 Cases Of Hypertensive Disorder Complicating Pregnancy

OBJECTIVE:To get the message of incidence hypertensive disordercomplicating pregnancy and it's effect to maternal and fetal.METHODS: To revew and analyzes 102 patients who visit in the first hospitalof JiLin UNIVERSITY and final diagnosised of hypertensive disordercomplicating pregnancy from 2001.5~2005.5。According to th6 edition of《obstetrics and gynecology》about separate criteria of hypertensive disordercomplicating pregnancy to 102 patients renewing classify,among them mildpre-eclampsia 18 cases,sever pre-eclampsia 68 cases,eclampsia 16 cases;according to whether having complication to divide them tocomplicationgroup ( 59-cases) and non complication group(43 cases);according tfactordiagnostic code of fetal grow th restriction dividing FGR group(37 cases) andnon FGR group(44 cases).Throughing compa rison between the above groupsabout incidence of the disease and correlatlive attenuated mumps virusvaccinefactor,we can initial clarity the disease and it's'complication whitchcaused negatively influence to maternal and fetal and also doing analysisabout the time of ermination of pregnancy。RESULTS:1.Different degree patients of hypertensive disorder complicatingpregnancy comparing habitation,civilization degree and times of antepartumcheck,mild pre-eclampsia patients who living in countryside are 6 cases, livingin city are 12 cases, sever pre-eclampsia patients who living in countryside are39 cases, living in city are 29 cases,eclampsia patients who living in countrysideare 12 cases, living in city are 3 cases, comparing three groups, P<0.05,there aresignificantly difference . Mild pre-eclampsia patients whose civilization degreeis high school and above are 15 cases, patients whose civilization degreebelowing junior middle shool are 2 casesand illiteracy 50% hemolysis ofcomplement cases, sever pre-eclampsia patients whose civilization degree ishigh school and above are 12 cases, patients whose civilization degree belowingjuni0r middle shool are 41 cases and illiteracy 5 cases;eclampsia patients whosecivilization degree is high school and above are 2 cases;patients whosecivilization degree belowing junior middle shool are 13 cases and illiteracy1cases, comparing three groups, P<0.05,there are significantly difference.Mildpre-eclampsia patients who have done antepartum check over 8 times are 13cases,fewer 8 times are3 cases,never chacked are 2 cases;sever pre-eclampsiapatients who have done antepartum check over 8 times are 13 cases, fewer 8times are20 cases, never chacked are 35 cases, eclampsia patients who havedone antepartum check over 8 times is none, fewer 8 times are 3 cases, neverchacked are 13 cases, comparing three groups, P<0.05, there are significantlydifference.2.Comparing different degree patients of hypertensive disordercomplicating pregnancy had complications( including obstetrics complicationand important organ to be involved in) and state of fetal to be born: Mildpre-eclampsia patients who combine complications are 4 cases, severpre-eclampsia patients who combine complications are 42 cases, eclampsiapatients who combine complications are 13 cases,through X2 test arriving at P<0.05. In mild pre-eclampsia patients there are term birth 13 cases,premature birth 4 cases, dead foetus and dead-birth 1 cases,FGR 1 cases, fetaldistress in uterus 2 cases,in sever pre-eclampsia patients there are term birth 20cases, premature birth 33 cases, dead foetus and dead-birth 15 cases,FGR 28cases, fetal distress in uterus 19 cases, in eclampsia patients there are term birth2cases, premature birth 9 cases, dead foetus and dead-birth 5 cases,FGR 8 cases,fetal distress in uterus 7 cases.Comparing the information of dead foetus anddead-birth ,FGR,fetal distress in uterus in three groups , arriving at that c,thereare difference in complications happen and state of new born postnatal in threegroups.3.Between complication group and non complication group , there areFGR 27 cases, dead foetus and dead-birth 27 cases in complication group ,innon complication group FGR,dead foetus and dead-birth respectively are 12cases and 4 cases.Compairing two groups , P<0.05, there are significantlydifference.In complication group and non complication group, delivering in 48hours respectively have 29 cases and 6 cases, delivering in 48~72 hoursrespectively have 22 cases and 18 cases, exceed 72 hours respectively have 8cases and 9 cases.Compairing two groups , P<0.05, there are significantlydifference.4.In 102 patients ,there are 81patients's neonate survival, among themthere FGR 29 cases, neonate who have normal body weigh'are 44cases.Compairing two groups every index including age,liver function,bloodcalcium,urea nitrogen,creatinine,carbon dioxide combining power,hemoglobin,platelet,urine protein,uric acid,fibrinogen。The result is thereare all have difference except age,ALT,AST and HGB.In FGR group , theaverage value of albumin,alkaline phosphatase,blood calcium respectively is29.77±8.12 g/L,129.43±66.14 U/L,1.92±0.19 mmol/L,2.8±0.6 g/L,noneof them is within normal limits.5.In 102 patients ,there are twin pregnancy 6 cases, obtain neonate total108 cases.Among them appearing 42 cases who anoxia after birth, deadfoetus and death from suffocation are 23 cases.There are 9 cases whose fetalage not achieve 28 weeks,15 cases whose fetal age between 28~32 weeks,26cases whose fetal age between 32~34weeks,40 cases whose fetal age between34~36 weeks, 15 cases whose fetal age between 36~40 weeks, those whoexceeded 40 weeks are 3 cases.There are the most people delivering in 34~36weeks. Those whose fetal age are 36~40 weeks their's'survival probabilityhigher than those whose fetal age are 34~36 weeks.Conclusion :1.Patients of hypertensive disorder complicating pregnancy in differenceserious level have significantly difference in habitation,habitation level andfrequency of antepartum chack .There are have necessary relationship betweenthe disease and living in countryside,lower civilization level ,fewer times ofantepartum chack.2. The probability of complication will be increase while the diseasegradually exacerbation .3. Following the pathogenetic condition aggravation,the incidence rate ofpremature birth,dead foetus and dead birth,FGR,fetal distress in uterus willbe increase.4.In complication , the incidence rate of dead foetus, dead birth and FGRhigher than in non complication group.5.Uterine-incision delivery is the best way in termination ofpregnancy .There are significantly difference between complication group andnon complication group,the rate of delivering whin 72 hours higher than noncomplication group.6. Albumin ,blood calcium and urine protein will have important reflectto fetal growth and development.7.The risk of asphyxia neonatorum and died will be decrease whengestational age achieve 34 weeks later.