The Study On The Correlation Between Infection Of HBV And Cholelithiasis

Objective To examine the correlation of infection of HBV and the formation of biliary sludge and cholelithiasis.Methods Gallbladder bile samples of 37 HBV-infection patients and 30 non-HBV-infection patients were investigated using direct and polarizing microscopy; and gallbladder bile samples of 31 HBV-infection patients and 25 non-HBV-infection patients were investigated, the total bile acids (TBA), total cholesterol (TC), phospholipid (PL),ionized calcium (Ca2+), unconjugated bilirubin (UCB) were determined.Results The result showed that biliary sludge was found in 11 cholelithiasis samples (100%). 12 samples of 31 HBV-infection patients were found biliary sludge (39%), 6 samples of 9 cases chronic hepatitis patients were found biliary sludge (67%), both were significantly higher than that in 2 samples of 25 cases non- HBV-infection patients (8%). Elevated levels of unconjugated bilirubin (UCB) and ionized calcium (Ca2+) were significantly higher than that in control groups. There were statistically significant differences between the two groups (P<0.01, P<0.05). Decreased levels of total bile acid (TBA) and total cholesterol (TC) were significant lower than...