Detection Of Peripheral Blood Lymphocyte Subsets In Early Sero-Resistant Syphilis Patients

Objective:Syphilis is one of the sexually transmitted diseases. The serological changes in the host are very complicated after treatment. Usually, the treponemal test will not become negative, but only the titer will descend. There will be three results of the nontreponemal test after treatment: (1) sero-negative: the serologic tests in ninety percent of the syphilis patients will become negative during 3 to 6 months after treatment; (2) sero-resistance: the skin lesions of the patient will soon disappear, but the nontreponemal test remains positive and its titer will not drop any more. This phenomenon is frequently detected in early syphilis patients. (3) sero-relapse: the serologic test which turns to negative after treatment becomes positive again, or the titer of the nontreponemal test increases more than 4 times. The sero-negative is the target of therapy, and the sero-relapse should be treated regularly again. However, for patients with sero-resistance, it is found in clinical work that these patients are given repeated treatment again but the titer of the nontreponemal test in those will not decline any more. This suggests that there be a lack of efficient therapy for the patients with sero-resistance. In the study, we have detected the...