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Effects Of Slw On The Operation-Transplanted Endometriosis And The Mechanism In Rats

Posted on:2007-10-20Degree:MasterType:Thesis
Country:ChinaCandidate:Y ChenFull Text:PDF
GTID:2144360185488261Subject:Pharmacology
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AIMThe model of endometriosis in SD rats by transplantation were established to find a suitable formula of SLW, through investigation the effect of the volume of the ectopic endometriotic tissue and the level of E2,P in serum. The effects of SLW on Endometriosis in SD rats were investigated in angiogenesis and the expression of vascular endothelial growth factor,tumor necrosis factor-alpha in ectopic endometriotic tissue, meanwhile study the mechanism of SLW's anti-angiogenesis treatment of endometriosis.METHODS1. The model of endometriosis in SD rats by transplantation were established after 4 weeks. Through investigation of the volume of the ectopic endometriotic tissue and the level of E2,P in serum, a suitable formula of SLW was found by orthogonal experimental design.2. The model of endometriosis in SD rats by transplantation were established after 4 weeks. Rats with established endometriosis were treated...
Keywords/Search Tags:SLW, angiogenesis, endometriosis, vascular endothelial growth factor, TNF-α
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