Objective To investigate the clinical effects of gamma knife radiosurgery and lumositine on cerebral meteastases.Methods The cases are divided into experiment and contral group in random from January 1st 2004 to May 1st 2006 in Taiyuan Gamma Knife Center.The experimental group includes 80 patients with 211 brain metastases are chemotherapied by lumostine after gamma knife radiosurgery.Lumostine is given to the patients every next 8 weeks.Three times chemotherapys are given to every course.The contral group of 87 patients with 205 malignant brain tumors are only treated by Gamma Knife radoisurgery.Then analyse the difference of the two group in software SPSS 12.0.Results The case group are higher than the contral in the reduce-ratio of tumors,Karnofsky rates and surrival-rate.But there is not diffence in complementary between the two groups.Conclusions Lumostine chemotherapy is an effective treatment after Gamma Knife radiosurgery for the cerebral meteastases and more effectual than the only radiosurgery.
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