Clinical Studies Of Irradiation With Gamma Knife Brain Edema

Objective:To explore some clinical characteristics and predictive factors for brain edema after gamma knife radiosurgery(GKS).Methods:365 nonfunctioanal incranial disease patients with follow-up treated by GKS were reviewed.Some clinical characteristics of brain edema after GKS were determined by descriptive statistical method.Then,the predictive factors for it were determined by X2 test and logistic regression model from the following variates:age,gender,KPS,peritarget edema condition,marginal radiodosage at isocurve surrounding 90% target volume,target location,mean maximal diameter of target and relationship between target and brain tissue.Results:Brain edema was observed in 22.2%patients of this group, with a more common frequency in the patients of glioma, ateriovenous malformation,cavernous malformation and meningoma.Of the brain edema, the most occurred in 2～4 month, and the near half brought the clinical symptom which had better effect to 20% mannitol combined by...