A Study On Radiosensitivity Of β-elemene To Squamous Cell Carcinoma Of Tongue Tca-8113 Cell Line In Vitro

Squamous cell carcinoma of tongue is the most common malignant tumor of Head and Neck system,that is treated by radiotherapy in peroperation term.Improving the radiosensitivity, not only radiate by the dose planed,but also reduce the organise injure,is the target we always have been making great efforts to get.Reasearch showed that carcinoma cells apoptosis increasing accompany the enhancing of radiosensitivity. Some researchers have taken the apoptosis level of carcinoma cells as a index to judge radiosensitivity.In order to increase the radiosensitivity of cells,The reshearchers have been trying hard to find out the methods to increase cell apoptosis level.Radiobiology has confirmed that there is much difference between different cell cycle phase in cell radiosensitivity.The cells arreste in phase G₂/M are the most radiosensitive. It is an important method to enhance carcinoma cell radiosensitivity and improve curative effect that inducing cells in phase G₁/S to move forward and arrest in phase G₂/M.Radiation sensitizing agents are one kind of chemosynthesising substance that they could improve carcinoma cells' radiosensitivity take less effect on normal cells.Since 1960s,many researches about radiosensitizer have been carried out and a series of in vivo and vitro protocols to test radiosensitization have been established.Though a great number of agents...