| Background and objective:The gastric carcinoma is one of the commonest malignant tumors and the mortality tops all the malignant tumors. The metastasis of gastric carcinoma occurs to 50 percent patients with gastric carcinoma, which is the main cause that leads to the low survival rate of the patients. The study of occurrence mechanism and molecular biology foundation of the invasion &metastasis of gastric carcinoma is very important to control the metastasis and improve the survival rate of the gastric carcinoma.A great deal of studies have shown that the high expression of IGF-1R lies in malignant nervous system tumor, liver cell carcinoma, breast...
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