Clinical Analysis Of Influence Of Ultrafiltration Upon Hemodialysis Adequcay In Hemodialysis

Objective: Analyze influence of ultrafiltration upon the kinetic modleling(Kt/V) andthe urea reduction ratio(URR) through observing ultrafiltrate volume,ultrafiltrate rate,bodyweight after dialysis,on-line Kt/V(JH-2000),Kt/V and URR of blood sample before and afterhemodialysis. At the same time the correlation between on-line Kt/V and real time blood-basedKt/V were compared and the influence of ultrafiltration upon hemodialysis adequacy wereinvestgated in order to provide some useful data on the research of hemodialysis adequacy inpatiens with renal failure.Method: 40 patiens with renal failure who had received maintenance hemodialysis in bloodpurification center of the First Affliated Hopital of Jinan University were investigated. Theinfluence of ultrafiltration on hemodialysis adequacy in the process of hemodialysis wereAnalyzed through observing and recording ultrafiltrate volume,ultrafiltrate rate,body weightafter hemodialysis,Kt/V and URR.Result: A strong correlation was found between blood-based Kt/V and conductivity-basedKt/V, the correlated statistics data were R=0.891, R~2=0.794, Y=0.102+0.904X. No obviouscorrelativity between the Kt/V and ultrafiltration volume could be observed. WhenUFR=15ml/h.kg positive correlativity between the Kt/V and ultrafiltration could be found, andwhen UFR＞15ml/h.kg negate correlativity between the Kt/V and ultrafiltration were observed.Conclusion: The results of our research suggest that when the speed of ultrafiltration isunder a threshold vahe(UFR=15ml/h), but when UFR＞15ml/h.kg the Kt/V will decrease alongwith ultrafiltration. The availability and applicability of on-line Kt/V(a new conductivitymethod) is also be proved.