This invention is use of alkaline method which preparation of chitosan by alkaline. In the course of chitosan preparation, it can make of high take off acetyl chitosan by use many alkaline methods to make up fresh lye and wipe off micromolecule sodium acetate in reaction process (deacyl variations 90%).The hydrogen in hydroxyl and amino is easy with chemical change and prepared corresponding derivatives which make chitosan materialized character better. This paper is concern about carboxymethylation on chitosan to prepare carboxymethyl chitosan. The preparation of carboxymethyl chitosan sliver is filtrated and optimized synthesize technics to the carboxymethyl of technology condition.The carboxymethyl chitosan sliver has been reported, whereas not see in periodontitis. So we study the foundation of carboxymethyl chitosan sliver on oral anaerobic bacterial. We have been got part of date which provides drug foundation for carboxymethy chitosan to apply periodontitis.
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