| Coronary atherosclerotic heart disease (CHD) is one of impor- tant type of atherosclerosis. It is the focal point to predict and prevent event of CHD. Use of noninvasive markers can predict the risk of cardiovascular disease in high-risk group early. It can provide reliable evidence for the treatment of CHD to decrease it's morbidity and mortality early. The ABI was originally used to identify lower-limb atherosclerosis. It has subsequently been shown to be an accurate and reliable marker of generalized athero- sclerosis. Cohort studies of abroad have shown the low ABI is independent dangerous factor and can predict the risk of both cardiovascular morbidity and mortality. Our study aimed to exa- mine the relation between ABI and the extent of the patient with angina pectoris. The ABI is measured by desk model sphygmomano- meter. Objective : This study aimed to examine the relation between ABI and the extent of the patient with angina pectoris. Ankle-brachial index (ABI) is measure by desk model sphygmomano- meter. Methods: We studied 106 patients who were hospitalized patients with angina cordis elected from Chinese-Japanese hospi- tal for coronary angiography. There are 69 of them who can be final diagnosis by electrocardiogram and symptom (include 12 myocard- ial infarction ) , and 24 patients with symptom ,13 of them have liability factor only. The study group consisted of 74 man (mean age 54.80±10.14 years) and 32 women (mean age 61.76±7.53 years), and all be measured arteria malleolaris blood pressure and arte- ria brachialis blood pressure three time with desk model sphygmo- manometer before coronary angiography. ABI is the ratio of the highest pressure of arteria malleolaris and brachialis. The his- tory of hypertension, diabetes and smoking were collected, and serum glucose, LDL-C, TC were write down. All patients were divid- ed into group of normal, 1-vessel disease, 2-vessel disease, 3-vessel disease (include left main disease) basised result of coronary angiography. Normal group is defi- nited the stenosis no more than 50% of mean vessels.1-vessel disease is definited the stenosis exceed 50% in one mean vessel; 2-vessel disease is definited the stenosis exceed 50% in two mean vessel; 3-vessel disease is definited the stenosis exceed 50% in three mean vessel or in left mean vessel. All disease in coronary were scored by Gensini method to evaluate dependability, specificity and sensi- tivity between ABI and coronary ar- tery stenosis, and evaluated Usefulness of ABI to predict the extent of CHD. Results: The ABI of normal group, 1- vessel disease, 2- vessel disease, 3- vessel disease is (1.07±0.16, 0.98±0.12,0.87±0.20, 0.81±0.18).The clinical data of this study show, There were significant differ- ences between ABI of 3- vessel disease (0.81±0.18) and 1 - vessel disease(0.98±0.12), normal group(1.07±0.16) p≤0.05;and there were significant differences between ABI of 3- vessel disease (0.81±0.18) and normal group(1.07±0.16) p≤0.01; There were significant differences between ABI of 2- vessel disease (0.87 ±0.20)and 1 - vessel disease(0.98±0.12), normal group(1.07±0.16) p≤0.05;There were no significant differences between ABI of the patients with 1–vessel disease(0.98±0.12) and normal group(1.07±0.16), p>0.05; and there were no significant diff- erences in ABI of 1–vessel disease (0.98±0.12)and 2-vessel disease(0.87±0.20), p>0.05. Correlation analysis were done between the LNCCS of disease in coronary and ABI of normal group, 1- vessel disease,2- vessel disease,3- vessel disease, all pati- ents. There were significant dependability between the LNCCS of disease in coronary and ABI of 3- vessel disease, 2- vessel disea- se,all patients. The coefficient correlation (r) is -0.74, -0.59, -0.63. The multiplicity show, ABI≤0.9,age and diabetes were the factor for predict the serious diseases of coronary. We divid- ed patients into two group with ABI>0.9 as the cut of point, and we find there were significant difference in mean age between ABI>0.9 group (53.21±10.74 years)and ABI≤0.9 group (64.10±10.02 years), P<0.05;There were significant difference in history of diabates between ABI>0.9 groupand ABI≤0.9 group, P<0.05. Con- clusion: There were significant differences between the patients with 3- vessel disease and 1–vessel disease, no vessel disease. We can find the significant dependability between ABI and the extent of coronery artery stenosis,it show that ABI≤0.9 can predict the extent of coronary artery stenosis of the patient with angina pectoris. Measurement of ABI with desk model sphygmomano- meter is simple, inex- pensive, and noninvasive,it very suitable for basic level hospital...
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