The Observation Of The Metabolism Change Of Trace Elements In Circumference Blood Of Preterm Infants And Rop Sufferers

ObjectiveTo observe the metabolism change of trace elements in circumference blood of preterm infants and infants who suffer from ROP.MethodTo select 30 preterm infants who had potential high risk facts of ROP as objects group and 18 normal infants as comparisons group. Then to mensurate the content of the trace elements (such as Mg, Cu, Zn, Mn, Se) in their serum respectively by atom spectrophotometer. We analyzed the result by statistics.ResultThe contents of Zn, Cu and Se in the serum from the 30 objects are respectively (0.75±0.22)mg/l ,(0.41±0.20)mg/l and (134.07±71.57)×10-3mg/l, but (0.55±0.12)mg/l, (0.65±0.194)mg/l and (202.92±44.71)×10-3 mg/l in the 18 comparisons. The contents of Cu and Se are significantly lower than those of the comparisons(P<0.01). While the content of Zn in objects'serum is significantly higher(P<0.01). And there is the same result between the infants that suffer from ROP and the comparison (P<0.01). The content of the trace elements upwards in the serum of infants who suffer from ROP is lower than the objects. But the result between the ROP patients and comparisons are not significantly different(P>0.01). The difference of contents of Mn and Mg in serum of the two groups has no statistics sense.ConclusionThe contents of Cu and Se in preterm infants who had high risk facts of ROP are obviously lower than that in the comparison. Among them the contents of Cu and Se in the ROP infants are also much lower while contents of Zn much higher. The result can reveal that the trace elements of preterm infants are scanty. Also the scarcity can be act a important role in ROP. We should supervise the trace elements of preterm infants in order to prevent the deficiencies of copper and selenium. Only in this way can we prevent the deficiencies of Cu and Se, so as to decrease the ROP risk and prevent the diseases.