Dependablity Research On Basic Syndrome Factors Of TCM About Angina Pectoris Of CHD

Background:Angina Pectoris Of CHD(Coronary Artery Disease) is an frequently cardiovascular disease, which is one of serious diseases to mankind. In this decades, according to the raising about living standard of our Country, the attack rate and death rate of CHD have raised obviously, and has becoming to be a main cause of death.The epidemiological investigation on CHD can make us understand the rule of many basic syndrome factors in different phase of disease, which meaningful to prophylaxis,judgement of clinical classification,treatment,improve prognosis of disease, and will helpful lower the attack rate,death rate and improve living quality.Professor Deng Tietao has raised a theory of CHD named "correlated of five solid organs,correlated between heart and spleen" , which has been proved good effect on clinical treatment about CHD. The aim of this research is to dig clinical syndrome in different phase of disease from lots of patients with CHD, and find the news about position and effect of heart and spleen, and approach the regularity of clinical basic syndrome in different phase, meanwhile, it can prove the theory raised by Pro. Deng Tietao , and to guide clinical treatment.Objective:To approach distribution regularity of syndrome factors of TCM in different phase about CHD patients, especially about the factors of heart and spleen, which will make some use of the clinical treatment.Methods:This research use clinical epidemiology methods to carry out a clinical epidemilolgic survey of syndromes of TCM about CHD patients in Guangzhou city.The research patients mainly comes from the heart center of traditional Chinese medical hospital of Guangdong province, from 2007.3 to 2007.12, according to diagnostic code and internalize standard choose valid patients and divide them into two groups, acute stage group and paracmasis stage group, to begin cross section investigations. Then observe and record the syndrome factors of TCM basised on "Information acquisition list of epidemiological investigation about CHD" .After finished checking about the data of list, then begin imput datas use two people and check it meanwhile to make sure exactly imput, now, we can get a database of syndrome factors of TCM about CHD, then use statistical analysis software SPSS 13.0 to analylize database and get results about syndrome factors, the main analytical method include descriptive statistics analysis and cluster analysis.Results:270 CHD patients be invided into two groups, acute stage group and paracmasis stage group, according to different disease phase, the first group contains 198 patients, the second group contains 72 patients, then begin research.1. Acute stage groupIt can be clustered into four groups:First: deficiency of vital energy and blood stasis,phlegm muddy(cold)essential resistance, heart and spleen are main disease locations, which occupied 38.9% in all acute stage group people.Second: deficiency of vital energy and blood stasis,phlegm muddy(hot)essential resistance, heart and spleen are main disease locations, which occupied 31.9% in all acute stage group people.Third:deficiency of both vital energy and yin,phlegm muddy essential resistance and blood stasis essential resistance, heart,spleen,lung and kidney are main disease locations, which occupied 17.7% in all acute stage group people.Fourth: deficiency of yangqi,phlegm muddy essential resistance and blood stasis essential resistance, heart,spleen,lung and kidney are main disease locations, which occupied 11.6% in all acute stage group people.2.paracmasis stage groupIt can be clustered into three groups:First: deficiency of both vital energy and yin,phlegm muddy(cold) essential resistance and blood stasis essential resistance, heart and spleen are main disease locations, which occupied 48.6% in all paracmasis stage group people.Second : deficiency of yangqi,phlegm muddy (cold) essential resistance and blood stasis essential resistance, heart,spleen,lung and kidney are main disease locations, which occupied 37.5% in all acute paracmasis group people.Third: deficiency of zhengqi,phlegm muddy (hot) essential resistance and blood stasis essential resistance, heart,spleen,lung,liver and kidney are main disease locations, which occupied 13.8% in all acute paracmasis group people.Conclusion:1. Asthenia in origin and asthenia in superficiality,inclusion of asthenia and sthenia are common appearance of CHD contains acute stage group and paracmasis stage group; asthenia syndrome is usually exists in paracmasis stage and sthenia syndrome is usually exists in acute stage, deficiency of heart and spleen is main appearance in asthenia syndrome and phlegm muddy and blood stasis are main appearance in sthenia syndrome.2. No matter acute stage group patients or paracmasis stage group patients, deficiency of heart and spleen,phlegm muddy and blood stasis always occupy main composition.3. Disease position essence refer to heart,spleen,lung,liver and kidney five solid organs, heart and spleen are the base and center of nosogenic to CHD.4. According to conclusion of this research, and combine together academic theory and clinical practice raisded by Professor Deng Tietao, we can catch one conclusion that penthemeron characteristics of CHD are consistent with the theory "correlated of heart and spleen" of "correlated among five solid organs" , which offer a theory base about clinical dialectical of CHD.5. This research has used multivariate analysis method to analysize database of four physical examinations of TCM about CHD, which mean that multivariate analysis method can become one of important methods in research on syndrome factors of TCM about CHD.