Expression Of Midkine, VEGF-A In Epithelial Ovariantumor Tissues And Clinical Significance

Objective: To investigate the expression and clinical significances of midkine(MK),vascular endothelial growth factor—A(VEGF—A) in epithelial ovarian tumors.Results: MK in epithelial ovarian cancer is higher in the expression, and benign tumors and ovarian tumor at the junction between a siginificant difference (P <0.01), and the clinical stage and tumor metastasis and related (P <0.05), But with the pathological type and age were not related (P> 0.05). VEGF-A high expression in epithelial ovarian cancer, and benign tumors and ovarian tumor at the junction between a significant difference, and clinical stages of tumor metastasis and related (P <0.05), and no pathological type and age Correlation (P> 0.05). MK and VEGF-A in epithelial ovarian cancer in the expression of consistency.Conclusion: (1),MK, VEGF-A may increase the expression of epithelial ovarian tumors and development play an important role.(2),MK, VEGF-A with epithelial ovarian cancer is closely related to the invasion and metastasis, the expression may become abnormal epithelial ovarian cancer prognostic indicators.(3),Epithelial ovarian cancer, MK, VEGF-A between the expression of consistency, suggesting that the two may be the way through the common epithelial ovarian cancer to participate in the occurrence and development and transfer process.