Research And Application Of Laparoscopic Operation In Colorectal Cancer

The laparoscopic operation as a minimally invasive techniqe in colorectal cancer has made great progress in the past 10 years. The technique has been accepted by more and more persons because of it's many advantages, such as smaller incision, less pain, less blood loss, quicker recovery, less complications, shorter hospital stay and so on. The research results showed that the laparoscopic operation had the same radical outcomes compared with conventional open method in colorectal cancer, and they had the same long-term survival rates. But in short-term outcome, the laparoscopic operation was better than the open operation, it could protect the immunity system of patients in colorectal cancer as well. The research results also showed that the pneumoperitoneum could influence biological behavior of tumor, increase the invasiveness of cancer cell and damage the parietal peritoneum in some degree. As a result, mesothelial cells showed clear cellular tumefaction, predominant spherical cellular form and intercellular clefts, all the changers induced exposure of the basal membrance. The rough surface and derangement of the hepatic vascular endothelial cells and intercellular clefts were observed after pneumoperitoneum. The mechanism of these changes isn't lucid. It needs further investigation in whether the interaction between these elements would cause the metastasis and relapse of the tumor. The laparoscopic technique also has some disadvantages, such as complex operating, long-time learning curve for doctors, expensive materials and so on. We believe that the laparoscopic operation will be accepted by more and more doctors and patients with the soluting of these problems.