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Clinical Research Of Danshen Injection In Treating Stable Coronary Heart Disease

Posted on:2010-09-10Degree:MasterType:Thesis
Country:ChinaCandidate:Y LiFull Text:PDF
GTID:2144360275479038Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Objective:Observation of Danshen injection soup of stable coronary heart disease angina clinical efficacy,and clinical research has shown that Danshen injection in patients with angina pectoris of coronary heart disease c-reactive protein(cRP),blood lipids, blood rheology,such as impact indicators and to study the mechanism of its efficacy.Methods:1.The clinical data of 80 cases of stable angina pectoris in patients with coronary heart disease are derived from Chinese medicine hospital in Hubei Province,in line with stable angina pectoris of coronary heart disease diagnostic criteria,were randomly divided into two groups,namely,treatment group,the control group.Two groups of patients with gender,age,course of illness,disease and angina combined graded by severity had no significant statistical difference(P>0.05),comparable.2.Use methods of 40 cases of the control group given crown expansion,improve myocardial ischemia in Western medicine, isosorbide dinitrate tablets 10mg,3 times a day,enteric-coated tablets of aspirin 75mg,day1,given to patients with hypertension Application of step-down treatment of angiotensin-converting enzyme inhibitor(ACEI) plus long-acting calcium antagonist(CCB), if necessary,the joint should be B receptor antagonist,combined hyperlipidemia in patients with diabetes and at the same time give Tiaozhi Jiangtang and treatment.40 cases of treatment group, the control group based on the suspended crown expansion,improve myocardial ischemia Tiaozhi western medicine and drugs,only patients given combined antihypertensive and hypoglycemic agents Danshen injection,500ml infusion time on the 1st.Both groups were suspended during treatment of other drug treatment of this disease,treatment time to 2 weeks to 1 course of treatment,two groups of patients were treated 2 treatment.3.Safety testing in the treatment of two groups of patients before and after blood,urine,stool routine,liver and kidney function and blood sugar,electrolyte tests to determine whether Danshen injection side effects and toxicity.4.Observation of curative effect of patients before and after treatment were observed symptoms and signs,serum indulge the same type of semi-acid,high-sensitivity C-reactive protein,blood lipids,blood theology,carotid artery intima-media thickness to improve the situation,and for statistical analysis. 5.A statistical method called measurement data into a set of data using the t test,data(x disabilities u) said that the count data using x2 test Ridit level of data analysis usedConclusion:Danshen injection on coronary heart disease in patients with stable angina pectoris marked clinical efficacy,can improve clinical symptoms of angina pectoris,signs,and no adverse reactions occurred.2.Danshen injection can reduce coronary heart disease stable angina patients with acid-type semi-hazy,high-sensitivity c-reactive protein, carotid intima-media thickness levels..3.Danshen injection can improve coronary heart disease in patients with stable angina pectoris and plasma lipid levels.
Keywords/Search Tags:Danshen injection, stable angina pectoris, clinical research
PDF Full Text Request
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