Study On The Constituents From Rabdosia Rubescens Hemsl.

Objective To obtain bioactive components from Rabdosia rubescens Hemsl. Methods To separate the constituents from Rabdosia rubescens by many chromatography methods, identify their structures by NMR,ESI-MS spectral analysis and TLC test. Result Fifteen compounds were abtained and elucidated as:α-amyrin (1), daucosterol(2), ursolic acid (3),β-sitosterol (4), enmenol-glucoside (5), lasiodonin (6), glucose (7), 2α,3α-dihydroxy-urs-12-en-28-oic acid (8), oridonin (9), pedalitin (10), inositol (11), ponicidin (12) , dayecrystals B (13), uracil (14), 1,2-benzenedicarboxylic acid, 1,2-bis(2-ethylhexyl) ester (15), 2-amino-3-phenylpropyl 2-benzamido-3-phenylpropanoate(16, 10mg) respectively. Conclusion 1. Among these compounds, compound 14 were obtained from the Rabdosia genus for the first time, compound 8,13 were obtained from this plant for the first time; 2. The compound of 1,2-benzenedicarboxylic acid, 1,2-bis(2-ethylhexyl) ester was came form experimental materials.