The Clinical Research About Pattern Of Syndrome And The Rule Of Differentiation Of Symptoms And Signs Of Essential Hypertension

Objectives:By investigating the correlated data of the essential hypertension(EH) hospitalized patients and statistical analyzing the pattern of syndrome of EH,to approach the rule about determine the EH treatment based on differentiation of symptoms and signs,to normalize the EH pattern of syndrome, to go further to recognize the difference between correlation factors of pattern of syndrome clearly,to formulate objective foundation for the prevention and cure of EH.Methods:We proceeded the clinical research by collecting and analyzing 409 cases(151 males,258 females)of EH between 5/2005～4/2009 in Guang Zhou University of TCM,all of which were chosen according to the inclusion criteria strictly. All of the data was entered to the computer,and was statistical analyzed using SPSS16.0 software.Results:1.The pattern of syndrome of EH are distributed into four types:hyperactivity of liver yang type(31.3%),type of deficiency of YIN leading to hyper activity of YANG(asthenic yin causing predominant yang type 16.1%),phlegmatic hygrosis type(46.2%),asthenia of both yin and yang type(6.4%),including accompanied symptoms and signs such as:blood stasis type(44.3%),hepatic fire type(9.0%),blood deficiency type(0.7%).2.Among the single pattern of syndrome,the amount of hyperactivity of liver yang type is larger than that of asthenic yin causing predominant yang type and phlegmatic hygrosis type,with significant difference in chi square test. Among the complex pattern of syndrome,the amount of asthenic yin causing predominant yang type,phlegmatic hygrosis type,asthenia of both yin and yang type accompanied with blood stasis type is much larger than that of hyperactivity of liver yang type,there is significant contrast between them. While the amount of hyperactivity of liver yang type accompanied with hepatic fire type is much larger than of the other types,There is significant contrast between them.3.The age comparison of all kinds of pattern of syndrome of EH:There is statistical significance in the contrast between excessive rising of liver-YANG type and the other types;the contrast between the type accompanied with blood stasis type and the one accompanied with the other types is statistical significance.4.The dependability contrast among different patterns of syndrome of EH accompanied with diabetes:the contrast between type of deficiency of YIN leading to hyper activity of YANG and phlegm-damp type is statistical significance.5.The dependability contrast among different patterns of syndrome of EH accompanied with coronary artery disease and cerebral apoplexy:The contrast between type of deficiency of YIN leading to hyper activity of YANG accompanied with coronary artery disease and type of excessive rising of liver-YANG accompanied with coronary artery disease is statistical significance;the contrast between the one accompanied with syndrome of blood stasis and the one accompanied with none is statistical significance.The contrast between phlegm-damp type accompanied with cerebral apoplexy and type of excessive rising of liver-YANG accompanied with cerebral apoplexy is statistical significance;the contrast between the one accompanied with syndrome of blood stasis and the one accompanied with the other types or none is statistical significance.6.The dependability contrast among different patterns of syndrome of EH accompanied with coronary artery disease and cerebral apoplexy:The contrast between type of deficiency of YIN leading to hyper activity of YANG accompanied with coronary artery disease and type of excessive rising of liver-YANG accompanied with coronary artery disease is statistical significance;the contrast between the one accompanied with syndrome of blood stasis and the one accompanied with none is statistical significance.The contrast between phlegm-damp type accompanied with cerebral apoplexy and type of excessive rising of liver-YANG accompanied with cerebral apoplexy is statistical significance;the contrast between the one accompanied with syndrome of blood stasis and the one accompanied with the other types or none is statistical significance.The dependability contrast among different patterns of syndrome of EH accompanied with renal inadequacy:The contrast between type of asthenia of both yin and yang accompanied with renal inadequacy and phlegm-damp type accompanied with renal inadequacy is statistical significance.Conclusion:1.The rule of pattern of syndrome of EH:distribution from many to few: phlegm-damp type>type of excessive rising of liver-YANG>type of deficiency of YIN leading to hyper activity of YANG>type of asthenia of both yin and yang. The rule of single pattern of syndrome of EH:type of excessive rising of liver-YANG>type of asthenia of both yin and yang Hype of asthenic yin causing predominant yang>phlegm-damp type.While among the patterns of syndrome be accompanied with EH,blood stasis type is the most,type of hepatic fire secondly,deficiency of both QI and blood least.Type of excessive rising of liver-YANG often accompany with type of hepatic fire,accompanying with blood stasis hardly can be seen,while the other types is just opposite,always accompanying with blood stasis type,seldom accompanying with type of hepatic fire.2.The developing rule of EH is that type of excessive rising of liver-YANG accompanied with type of hepatic fire or accompanied with nothing is often seen at the early stage;type of asthenic yin causing predominant yang is often seen at the intermediate stage,type of asthenia of both yin and yang and phlegm-damp type accompanied with blood stasis is often seen at the late stage.3.We can consider EH accompanied with diabetes as an objective index to distinguish type of deficiency of YIN leading to hyper activity of YANG.4.We can consider EH accompanied with coronary artery disease and cerebral apoplexy as reference standard to distinguish EH accompanied with blood stasis type and EH do not accompanied with type of hepatic fire.5.Deficiency syndrome of both YIN and YANG EH hurt renal function mainly. We can consider renal vascular hypertension as reference standard to distinguish deficiency syndrome of both YIN and YANG.